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Khosla Ventures AI portfolio in San Francisco

Vinod Khosla's firm — deeptech, climate, healthcare, and contrarian software bets. Filtered to AI companies headquartered in San Francisco.

Built from a search like: “Khosla Ventures-backed AI companies in San Francisco”

Ranked by current headcount across Khosla Ventures-backed AI companies in San Francisco. Refreshed daily.

  1. 1
    OpenAI· San Francisco, California, United States
    • Series unknown
    • 7.8k employees
    • Founded 2015
  2. 2
    NewLimit· South San Francisco, California, United States
    • Convertible note
    • 50 employees
    • Founded 2022
  3. 3
    NOETIK· South San Francisco, California, United States
    • Grant
    • 45 employees
    • Founded 2022
  4. 4
    Vivodyne· San Francisco Bay Area
    • Seed
    • 39 employees
    • Founded 2020
  5. 5
    Faeth Therapeutics· San Francisco, California, United States
    • Series A
    • 28 employees
    • Founded 2019
  6. 6
    Probably Genetic· San Francisco, California, United States
    • Series unknown
    • 24 employees
    • Founded 2019
  7. 7
    Moonwalk Biosciences· South San Francisco, California, United States
    • Series A
    • 21 employees
    • Founded 2022
  8. 8
    Atomwise· San Francisco, California, United States
    • Series D
    • 18 employees
    • Founded 2012
  9. 9
    Menten AI· San Francisco, California, United States
    • Seed
    • 18 employees
    • Founded 2020
  10. 10
    IgGenix, Inc· South San Francisco, California, United States
    • Series B
    • 6 employees
    • Founded 2019
  11. 11
    Vero Bioscience, Inc.· San Francisco Bay Area
    • Seed
    • 5 employees
    • Founded 2025
  12. 12
    Fountain Therapeutics· South San Francisco, California, United States
    • Series A
    • 4 employees
    • Founded 2018

Khosla Ventures-backed AI companies in San Francisco

The list above ranks Khosla Ventures-backed AI companies headquartered in San Francisco by current headcount, drawn from public LinkedIn and Crunchbase records. With 12 matching companies in our index, you can see exactly where Khosla Ventures’s AI thesis has landed in San Francisco.

Three filters — investor, industry, city — narrow the field to a tight cluster of operators with overlapping incentives. They share a thesis, a network, and a market. Hiring from this list usually means hiring someone already inside the Khosla Ventures AI world in San Francisco.

Refolk converts this list into a live search. Ask for “Khosla Ventures AI companies in San Franciscohiring senior engineers” or “founders of Khosla Ventures-backed AI companies in San Francisco who left in the last year” and Refolk returns a ranked shortlist.

How this list is built

Refolk pulled AI companies headquartered in San Francisco whose disclosed Crunchbase investor list includes Khosla Ventures, ranked them by current employee count, and kept those with at least 3 employees. The list refreshes once a day.

Last refreshed: Thu, 07 May 2026 08:07:10 GMT

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