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Andreessen Horowitz AI portfolio in San Francisco

Multi-stage venture firm investing across consumer, enterprise, fintech, and crypto. Filtered to AI companies headquartered in San Francisco.

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Built from a search like: “Andreessen Horowitz-backed AI companies in San Francisco”

Ranked by current headcount across Andreessen Horowitz-backed AI companies in San Francisco. Refreshed daily.

  1. 1
    OpenAI· San Francisco, California, United States
    • Series unknown
    • 9.4k employees
    • Founded 2015
  2. 2
    insitro· South San Francisco, California, United States
    • Series C
    • 255 employees
    • Founded 2018
  3. 3
    Cartography Biosciences· South San Francisco, California, United States
    • Series unknown
    • 67 employees
    • Founded 2020
  4. 4
    Arena· San Francisco, California, United States
    • Series A
    • 62 employees
    • Founded 2025
  5. 5
    Rezo Therapeutics· San Francisco, California, United States
    • Series A
    • 44 employees
    • Founded 2021
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Andreessen Horowitz-backed AI companies in San Francisco

The list above ranks Andreessen Horowitz-backed AI companies headquartered in San Francisco by current headcount, drawn from public LinkedIn and Crunchbase records. With 11 matching companies in our index, you can see exactly where Andreessen Horowitz’s AI thesis has landed in San Francisco.

Three filters - investor, industry, city - narrow the field to a tight cluster of operators with overlapping incentives. They share a thesis, a network, and a market. Hiring from this list usually means hiring someone already inside the Andreessen Horowitz AI world in San Francisco.

Refolk converts this list into a live search. Ask for “Andreessen Horowitz AI companies in San Franciscohiring senior engineers” or “founders of Andreessen Horowitz-backed AI companies in San Francisco who left in the last year” and Refolk returns a ranked shortlist.

How this list is built

Refolk pulled AI companies headquartered in San Francisco whose disclosed Crunchbase investor list includes Andreessen Horowitz, ranked them by current employee count, and kept those with at least 3 employees. The list refreshes once a day.

Last refreshed: Sun, 21 Jun 2026 09:39:26 GMT

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