Sequoia Capital AI portfolio in San Francisco
Storied venture firm backing seed through pre-IPO across software and infrastructure. Filtered to AI companies headquartered in San Francisco.
Built from a search like: “Sequoia Capital-backed AI companies in San Francisco”
Ranked by current headcount across Sequoia Capital-backed AI companies in San Francisco. Refreshed daily.
- 1OpenAI· San Francisco, California, United States
- Series unknown
- 7.8k employees
- Founded 2015
- 2Xaira Therapeutics· South San Francisco, California, United States
- Series A
- 192 employees
- Founded 2023
- 3Algen Biotechnologies· San Francisco, California, United States
- Seed
- 16 employees
- Founded 2018
- 4Stemcentrx, Inc.· South San Francisco, California, United States
- Series G
- 6 employees
- Founded 2008
Sequoia Capital-backed AI companies in San Francisco
The list above ranks Sequoia Capital-backed AI companies headquartered in San Francisco by current headcount, drawn from public LinkedIn and Crunchbase records. With 4 matching companies in our index, you can see exactly where Sequoia Capital’s AI thesis has landed in San Francisco.
Three filters — investor, industry, city — narrow the field to a tight cluster of operators with overlapping incentives. They share a thesis, a network, and a market. Hiring from this list usually means hiring someone already inside the Sequoia Capital AI world in San Francisco.
Refolk converts this list into a live search. Ask for “Sequoia Capital AI companies in San Franciscohiring senior engineers” or “founders of Sequoia Capital-backed AI companies in San Francisco who left in the last year” and Refolk returns a ranked shortlist.
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Last refreshed: Thu, 07 May 2026 08:01:09 GMT
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