Sequoia Capital portfolio AI companies

Storied venture firm backing seed through pre-IPO across software and infrastructure. Filtered to companies in AI.

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Built from a search like: “Sequoia Capital-backed AI companies”

Ranked by current headcount across Sequoia Capital-backed AI companies. Refreshed daily.

1
OpenAI· San Francisco, California, United States
OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. AI is an extremely powerful tool that must be created with safety and human needs at its core. OpenAI is dedicated to putting that alignment of interests first — ahead of profit.To achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity. Our investment in diversity, equity, and inclusion is ongoing, executed through a wide range of initiatives, and championed and supported by leadership.At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.
- Series unknown
- 10.2k employees
- Founded 2015
2
Natera· Austin, Texas, United States
NateraTM is a global leader in cell-free DNA and precision medicine, dedicated to oncology, women’s health, and organ health. We aim to make personalized genetic testing and diagnostics part of the standard-of-care to protect health and inform earlier, more targeted interventions that help lead to longer, healthier lives. Natera’s tests are supported by more than 325 peer-reviewed publications that demonstrate excellent performance. Natera operates ISO 13485-certified and CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in Austin, Texas, and San Carlos, California, and through Foresight Diagnostics, its subsidiary, operates an ISO 27001-certified and CAP-accredited laboratory certified under CLIA in Boulder, Colorado. Please be advised that Natera will only reach out to candidates with an @natera.com email domain. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.https://www.natera.com/privacy/
- Post-IPO equity
- 5.9k employees
- Founded 2004
3
Anthropic
We're an AI research company that builds reliable, interpretable, and steerable AI systems. Our first product is Claude, an AI assistant for tasks at any scale.Our research interests span multiple areas including natural language, human feedback, scaling laws, reinforcement learning, code generation, and interpretability.
- Series H
- 5.3k employees
- Founded 2021
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4
Guardant Health· Palo Alto, California, United States
Guardant Health is a leading precision medicine company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, we're transforming patient care by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant® tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer.Important Note for Job Applicants:Guardant Health is aware of recruiting scams where unauthorized individuals use the company's name in fraudulent emails, job postings, and social media messages. Please note that Guardant Health will never ask for money or credit card information during the job application process, nor does the company communicate with candidates via online chatrooms or personal email accounts such as Gmail or Hotmail.
- Post-IPO debt
- 4.7k employees
- Founded 2012
5
Novotech· Singapore, Singapore
Novotech is a globally recognized full-service clinical research organization (CRO) and scientific advisory company that provides biotech and small- to mid-sized pharma companies an accelerated path to market since 1997. With a global footprint spanning 30+ offices across the Asia-Pacific region, North America, and Europe, and partnerships with 5,000+ trial sites, Novotech offers unparalleled access to key clinical trial destinations and diverse patient populations.Novotech leverages its therapeutic and regulatory expertise, client-centric service model, local market insights, and advanced analytical tools to expedite patient recruitment, enhance trial efficiencies, and bring life-changing therapies to market faster. This work has been recognized by awards such as the Frost & Sullivan CRO Company of the Year, which Novotech has received for 19 consecutive years. For more information or to speak to an expert team member visit www.Novotech-CRO.com
- Private equity
- 2.2k employees
- Founded 1997

6
ElevenLabs· London, England, United Kingdom
ElevenLabs is transforming human-technology interaction with AI research and products.ElevenAgents enables businesses to deliver seamless and intelligent customer experiences, with the integrations, testing, monitoring, and reliability necessary to deploy voice and chat agents at scale.ElevenCreative empowers creators and marketers to generate and edit speech, music, image, and video across 70+ languages.ElevenAPI gives developers access to our leading AI audio foundational models.These platforms are powered by our leading AI research. We developed the first human-like AI voice model, then expanded into dubbing, transcription, music, sound effects, and speech-to-speech.We serve millions of users and thousands of businesses from the fastest growing startups to the largest enterprises like Harvey, Deutsche Telekom and Meta.
- Secondary
- 1.1k employees
- Founded 2022
7
BridgeBio· Palo Alto, California, United States
We exist to bring transformative medicines to people living with genetic conditions. Our model pairs advances in genetic science with an entrepreneurial mindset, enabling us to move with urgency and translate scientific possibility into real-world impact.We’re building leaders as well as transformative medicines, and we’re looking for people driven to push boundaries, solve hard problems, and help patients who can’t wait any longer.
- Post-IPO equity
- 1k employees
- Founded 2014
8
MEDGENOME· Bengaluru, Karnataka, India
MedGenome is a global genomics and precision diagnostics company focused on enabling accurate, early and actionable diagnosis through advanced genomic science. We operate South Asia’s largest CAP-accredited genetic testing laboratory and offer a comprehensive test menu of more than 1,300 genetic assays across key disease areas.Our diagnostic capabilities span rare inherited disorders, oncology, reproductive health, infectious diseases and preventive wellness. By integrating next-generation sequencing technologies with proprietary assays and AI-enabled bioinformatics platforms, MedGenome delivers high-quality genomic insights that support clinicians in complex clinical decision-making.Founded with a vision to make genomic healthcare affordable and accessible, MedGenome has built deep scientific and clinical expertise backed by extensive research and global collaborations. Our work is supported by a strong research foundation with hundreds of peer-reviewed scientific publications, reflecting our commitment to evidence-based diagnostics and innovation.MedGenome serves clinicians and healthcare institutions across hundreds of locations in India and multiple countries worldwide. Our team of scientists, genome analysts, bioinformaticians and clinical experts works closely with healthcare providers to ensure test accuracy, clinical relevance and timely reporting.We are driven by a commitment to continuous innovation, quality and education. From developing in-house genomics solutions to advancing awareness around genetic testing, MedGenome plays an active role in shaping the future of precision medicine.At MedGenome, every genome decoded strengthens our mission to improve patient outcomes, support clinicians with reliable insights and transform healthcare through the power of genomics.
- Series E
- 1k employees
- Founded 2013
9
Neuralink· Austin, Texas, United States
Neuralink is a neurotechnology company building a generalized input/output platform for the brain. Our work has the potential to restore autonomy to those with unmet medical needs and fundamentally transform how humans interact with the world.Our core technology is an implantable brain-computer interface with ultra-thin, flexible electrode threads placed precisely by a surgical robot, enabling high-bandwidth, bidirectional interaction with neural signals.We’ve received multiple FDA Breakthrough Device designations and are conducting clinical trials around the world. Trial participants are exploring how our implant could enhance their daily lives — controlling digital devices like computers and smartphones, operating physical devices like robotic arms and wheelchairs, and translating thought directly into speech and text.Developing brain-computer interfaces is an interdisciplinary challenge, and we’re looking for exceptional talent across engineering, science, and operations. Explore opportunities to contribute to our mission at neuralink.com/careers.
- Series unknown
- 701 employees
- Founded 2016
10
Ameritox· Columbia, Maryland, United States
Ameritox helped pioneer the prescription drug monitoring necessary to address the national epidemic of prescription drug misuse, abuse and diversion. As a trusted leader in medication monitoring, Ameritox provides medical and business professionals with health care solutions that can help improve patient care and prevent tragedy. Ameritox has also established a service, Ingenuity Health, which uses similar drug monitoring science to provide highly reliable data that helps doctors and behavioral health specialists improve treatment for patients diagnosed with serious mental illness. Ameritox, headquartered in Maryland and has a laboratory facilities in Greensboro, N.C. Ameritox can be found online at ameritox.com and on Twitter @Ameritox.Ameritox, LLC is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any characteristic protected by law.
- Series unknown
- 302 employees
- Founded 1996

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Sequoia Capital’s AI portfolio

The list above ranks Sequoia Capital-backed AI companies by current headcount, drawn from public LinkedIn and Crunchbase records. 33 matching companies in Refolk’s index give you a quick read on where Sequoia Capital has gone deepest in the AI space.

Sequoia Capital’s AI bets tend to share a thesis. The engineers, ML researchers, and founders inside these companies are often building the same primitives - and they show up in AI talent pools across the next decade.

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How this list is built

Refolk pulled AI companies whose disclosed Crunchbase investor list includes Sequoia Capital, ranked them by current employee count, and kept those with at least 5 employees. The list refreshes once a day.

Last refreshed: Wed, 05 Aug 2026 09:51:59 GMT

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