Lightspeed Venture Partners portfolio AI companies

Multi-stage venture firm with deep practices in enterprise, consumer, and fintech. Filtered to companies in AI.

Built from a search like: “Lightspeed Venture Partners-backed AI companies”

Ranked by current headcount across Lightspeed Venture Partners-backed AI companies. Refreshed daily.

1
Natera· Austin, Texas, United States
- Post-IPO equity
- 5.7k employees
- Founded 2004
2
Anthropic
- Series G
- 5.3k employees
- Founded 2021
3
Guardant Health· Palo Alto, California, United States
- Post-IPO debt
- 4.3k employees
- Founded 2012
4
ElevenLabs· London, England, United Kingdom
- Series D
- 752 employees
- Founded 2022
5
Neuralink· Fremont, California, United States
- Series unknown
- 628 employees
- Founded 2016
6
Personalis, Inc.· Fremont, California, United States
- Post-IPO equity
- 384 employees
- Founded 2011
7
Ultima Genomics· Fremont, California, United States
- Series unknown
- 303 employees
- Founded 2016
8
Karius· Redwood City, California, United States
- Series C
- 201 employees
- Founded 2014
9
Xaira Therapeutics· South San Francisco, California, United States
- Series A
- 192 employees
- Founded 2023
10
Olema Oncology· San Francisco, California, United States
- Post-IPO equity
- 157 employees
- Founded 2007
11
Enlaza Therapeutics· San Diego, California, United States
- Series unknown
- 62 employees
- Founded 2020
12
Arena· San Francisco, California, United States
- Series A
- 58 employees
- Founded 2025
13
TRIANA Biomedicines· Lexington, Massachusetts, United States
- Series B
- 56 employees
- Founded 2019
14
Seismic Therapeutic· Watertown, Massachusetts, United States
- Series B
- 51 employees
- Founded 2020
15
Radicle Science· San Diego, California, United States
- Seed
- 40 employees
- Founded 2020
16
GTM Research· United States
- Series unknown
- 38 employees
- Founded 2007
17
doubleAI
- Series A
- 37 employees
- Founded 2023
18
3T Biosciences· South San Francisco, California, United States
- Series A
- 29 employees
- Founded 2017
19
Satellite Bio· Cambridge, Massachusetts, United States
- Series A
- 23 employees
- Founded 2019
20
Forty Seven Inc.· Menlo Park, California, United States
- Post-IPO equity
- 23 employees
- Founded 2015
21
Protego Bio· San Diego, California, United States
- Series B
- 23 employees
- Founded 2011
22
SENSEERA· Jerusalem District, Israel
- Seed
- 20 employees
- Founded 2020
23
Epinomics - Part of 10x Genomics· Pleasanton, California, United States
- undisclosed
- 5 employees
- Founded 2013

Lightspeed Venture Partners’s AI portfolio

The list above ranks Lightspeed Venture Partners-backed AI companies by current headcount, drawn from public LinkedIn and Crunchbase records. 23 matching companies in our index give you a quick read on where Lightspeed Venture Partners has gone deepest in the AI space.

Lightspeed Venture Partners’s AI bets tend to share a thesis. The engineers, ML researchers, and founders inside these companies are often building the same primitives — and they show up in AI talent pools across the next decade.

Refolk converts this list into a live search. Ask for “Lightspeed Venture Partners AIcompanies hiring senior engineers” or “founders of Lightspeed Venture Partners-backed AIcompanies” and Refolk returns a fresh ranked shortlist.

How this list is built

Refolk pulled AI companies whose disclosed Crunchbase investor list includes Lightspeed Venture Partners, ranked them by current employee count, and kept those with at least 5 employees. The list refreshes once a day.

Last refreshed: Thu, 07 May 2026 06:08:04 GMT

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