Khosla Ventures portfolio AI companies

Vinod Khosla's firm — deeptech, climate, healthcare, and contrarian software bets. Filtered to companies in AI.

Built from a search like: “Khosla Ventures-backed AI companies”

Ranked by current headcount across Khosla Ventures-backed AI companies. Refreshed daily.

1
OpenAI· San Francisco, California, United States
- Series unknown
- 7.8k employees
- Founded 2015
2
Guardant Health· Palo Alto, California, United States
- Post-IPO debt
- 4.3k employees
- Founded 2012
3
Ultima Genomics· Fremont, California, United States
- Series unknown
- 303 employees
- Founded 2016
4
Loyal· Dallas, Texas, United States
- Series C
- 205 employees
- Founded 2020
5
Karius· Redwood City, California, United States
- Series C
- 201 employees
- Founded 2014
6
Opentrons Labworks Inc.· New York, New York, United States
- Series D
- 201 employees
- Founded 2014
7
Editas Medicine· Cambridge, Massachusetts, United States
- Post-IPO equity
- 183 employees
- Founded 2013
8
eGenesis· Cambridge, Massachusetts, United States
- Series D
- 142 employees
- Founded 2015
9
Relation· Greater London, England, United Kingdom
- Series unknown
- 124 employees
- Founded 2019
10
Cellino· Cambridge, Massachusetts, United States
- Grant
- 110 employees
- Founded 2017
11
Deep Genomics· Toronto, Ontario, Canada
- Series C
- 106 employees
- Founded 2014
12
BioAge Labs· Emeryville, California, United States
- Post-IPO equity
- 97 employees
- Founded 2015
13
National Cancer Research Institute (NCRI)· London, England, United Kingdom
- Series A
- 78 employees
- Founded 2001
14
Mascoma LLC· Lebanon, New Hampshire, United States
- Debt
- 75 employees
- Founded 2006
15
Inflammatix, Inc.· Sunnyvale, California, United States
- Series E
- 74 employees
- Founded 2016
16
Synex· Toronto, Ontario, Canada
- Series A
- 63 employees
- Founded 2017
17
Scipher Medicine· Burlington, Massachusetts, United States
- Series D
- 60 employees
- Founded 2015
18
Ochre Bio· Oxford, England, United Kingdom
- Series A
- 60 employees
- Founded 2019
19
Genesis AI
- Seed
- 59 employees
- Founded 2024
20
Cellular Intelligence | formerly Somite AI· Boston, Massachusetts, United States
- Series unknown
- 58 employees
- Founded 2023
21
Prellis Biologics· Berkeley, California, United States
- Series C
- 55 employees
- Founded 2016
22
Ukko· Tel Aviv-Yafo, Tel Aviv District, Israel
- Series C
- 55 employees
- Founded 2016
23
Lightship· Durham, North Carolina, United States
- Series C
- 53 employees
- Founded 2018
24
Kernel· Culver City, California, United States
- Series unknown
- 52 employees
- Founded 2016
25
BioConsortia, Inc.· Davis, California, United States
- Series unknown
- 50 employees
- Founded 2014

Khosla Ventures’s AI portfolio

The list above ranks Khosla Ventures-backed AI companies by current headcount, drawn from public LinkedIn and Crunchbase records. 51 matching companies in our index give you a quick read on where Khosla Ventures has gone deepest in the AI space.

Khosla Ventures’s AI bets tend to share a thesis. The engineers, ML researchers, and founders inside these companies are often building the same primitives — and they show up in AI talent pools across the next decade.

Refolk converts this list into a live search. Ask for “Khosla Ventures AIcompanies hiring senior engineers” or “founders of Khosla Ventures-backed AIcompanies” and Refolk returns a fresh ranked shortlist.

How this list is built

Refolk pulled AI companies whose disclosed Crunchbase investor list includes Khosla Ventures, ranked them by current employee count, and kept those with at least 5 employees. The list refreshes once a day.

Last refreshed: Thu, 07 May 2026 06:45:06 GMT

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