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Y Combinator SaaS portfolio in San Francisco

The most prolific seed accelerator in the world, batch class twice a year. Filtered to SaaS companies headquartered in San Francisco.

Built from a search like: “Y Combinator-backed SaaS companies in San Francisco”

Ranked by current headcount across Y Combinator-backed SaaS companies in San Francisco. Refreshed daily.

  1. 1
    Airbnb· San Francisco, California, United States
    • Post-IPO debt
    • 69.2k employees
    • Founded 2007
  2. 2
    Twitch· San Francisco, California, United States
    • Series C
    • 17.5k employees
    • Founded 2011
  3. 3
    Stripe· South San Francisco, California, United States
    • Secondary
    • 14.7k employees
    • Founded 2010
  4. 4
    Rippling· San Francisco, California, United States
    • Series G
    • 7.2k employees
    • Founded 2016
  5. 5
    Scale AI· San Francisco, California, United States
    • Corporate
    • 6.5k employees
    • Founded 2016
  6. 6
    Reddit, Inc.· San Francisco, California, United States
    • Series F
    • 4.7k employees
    • Founded 2005
  7. 7
    Gusto· San Francisco, California, United States
    • Series A
    • 4.4k employees
    • Founded 2011
  8. 8
    Clipboard· San Francisco, California, United States
    • Series C
    • 3.4k employees
    • Founded 2016
  9. 9
    Instawork· San Francisco, California, United States
    • Series D
    • 2.3k employees
    • Founded 2016
  10. 10
    Homebase· San Francisco, California, United States
    • Series D
    • 1.8k employees
    • Founded 2014
  11. 11
    Magic· San Francisco, California, United States
    • Series unknown
    • 1.8k employees
    • Founded 2014
  12. 12
    Vanta· San Francisco, California, United States
    • Series D
    • 1.7k employees
    • Founded 2018
  13. 13
    Webflow· San Francisco, California, United States
    • Series unknown
    • 1.7k employees
    • Founded 2013
  14. 14
    Checkr, Inc.· San Francisco, California, United States
    • undisclosed
    • 1.7k employees
    • Founded 2014
  15. 15
    6sense· San Francisco, California, United States
    • Debt
    • 1.6k employees
    • Founded 2013
  16. 16
    Faire· San Francisco, California, United States
    • Secondary
    • 1.5k employees
    • Founded 2017
  17. 17
    Zapier· San Francisco, California, United States
    • Series unknown
    • 1.4k employees
    • Founded 2011
  18. 18
    PagerDuty· San Francisco, California, United States
    • Post-IPO debt
    • 1.3k employees
    • Founded 2009
  19. 19
    Zip· San Francisco, California, United States
    • Series D
    • 1.2k employees
    • Founded 2020
  20. 20
    Courier· San Francisco, California, United States
    • Series B
    • 1.1k employees
    • Founded 2019
  21. 21
    Jasper· San Francisco, California, United States
    • Series A
    • 1k employees
    • Founded 2020
  22. 22
    Yummy· San Francisco, California, United States
    • Series A
    • 1k employees
    • Founded 2020
  23. 23
    Ironclad· San Francisco, California, United States
    • Series E
    • 800 employees
    • Founded 2014
  24. 24
    Benchling· San Francisco, California, United States
    • Series F
    • 794 employees
    • Founded 2012
  25. 25
    Niantic, Inc.· San Francisco, California, United States
    • Series D
    • 692 employees
    • Founded 2011

Y Combinator-backed SaaS companies in San Francisco

The list above ranks Y Combinator-backed SaaS companies headquartered in San Francisco by current headcount, drawn from public LinkedIn and Crunchbase records. With 867 matching companies in our index, you can see exactly where Y Combinator’s SaaS thesis has landed in San Francisco.

Three filters — investor, industry, city — narrow the field to a tight cluster of operators with overlapping incentives. They share a thesis, a network, and a market. Hiring from this list usually means hiring someone already inside the Y Combinator SaaS world in San Francisco.

Refolk converts this list into a live search. Ask for “Y Combinator SaaS companies in San Franciscohiring senior engineers” or “founders of Y Combinator-backed SaaS companies in San Francisco who left in the last year” and Refolk returns a ranked shortlist.

How this list is built

Refolk pulled SaaS companies headquartered in San Francisco whose disclosed Crunchbase investor list includes Y Combinator, ranked them by current employee count, and kept those with at least 3 employees. The list refreshes once a day.

Last refreshed: Thu, 07 May 2026 08:00:43 GMT

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