Top Data infrastructure companies in San Francisco

Databases, warehouses, lakes, pipelines, and observability for production data. Filtered to companies headquartered in San Francisco.

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Ranked by current headcount across Data infrastructure companies headquartered in San Francisco. Refreshed daily.

1
Upwork· San Francisco, California, United States
Upwork is the world’s work marketplace that connects businesses with independent talent from across the globe. We serve everyone from one-person startups to large, Fortune 100 enterprises with a powerful, trust-driven platform that enables companies and talent to work together in new ways that unlock their potential. Our talent community on Upwork encompasses more than 10,000 skills in categories including website & app development, creative & design, customer support, finance & accounting, consulting, and operations.
- Post-IPO debt
- 177.7k employees
- Founded 2015
2
Salesforce· San Francisco, California, United States
We're the #1 AI CRM—where humans with agents drive customer success together with AI, data, and Customer 360 apps on one platform.Privacy Statement: http://www.salesforce.com/company/privacy/
- Post-IPO debt
- 88.9k employees
3
DoorDash· San Francisco, California, United States
At DoorDash, our mission to empower local economies shapes how our team members move quickly and always learn and reiterate to support merchants, Dashers and the communities we serve. We are a technology and logistics company that started with door-to-door delivery, and we are looking for team members who can help us go from a company that is known for delivering food to a company that people turn to for any and all goods. DoorDash is growing rapidly and changing constantly, which gives our team members the opportunity to share their unique perspectives, solve new challenges, and own their careers. Our leaders seek the truth and welcome big, hairy, audacious questions. We are grounded in our company values, and we make intentional decisions that are both logical and display empathy for our range of users—from Dashers to Merchants to Customers.
- Post-IPO debt
- 82.4k employees
- Founded 2013
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4
Airbnb· San Francisco, California, United States
Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays, experiences and services that make it possible for guests to connect with communities in a more authentic way.
- Post-IPO debt
- 72.2k employees
- Founded 2007
5
N/A· San Francisco, California, United States
IT Services and IT Consulting
- 29.6k employees
- Founded 1988

6
Globant· San Francisco, California, United States
At Globant, we create the digitally-native products that people love. We bridge the gap between businesses and consumers through technology and creativity, leveraging our experience as an AI powerhouse. We dare to digitally transform organizations and strive to delight their customers.- We have more than 30,000 employees and are present in 33 countries across 5 continents, working for companies like Google, Electronic Arts, and Santander, among others.- We were named a Worldwide Leader in AI Services (2023) and a Worldwide Leader in CX Improvement Services (2020) by IDC MarketScape report.- We are the fastest-growing IT brand and the 5th strongest IT brand globally (2024), according to Brand Finance.- We were featured as a business case study at Harvard, MIT, and Stanford.- We are active members of The Green Software Foundation (GSF) and the Cybersecurity Tech Accord.For more information, visit https://bit.ly/globant_comFollow us:http://www.twitter.com/globanthttp://www.youtube.com/Globanthttp://www.facebook.com/Globanthttps://instagram.com/Globanthttps://www.tiktok.com/@globant
- post ipo secondary
- 28.1k employees
- Founded 2003
7
Instacart· San Francisco, California, United States
Instacart is a leading grocery technology company that partners with more than 2,200 retail banners – representing nearly 100,000 stores – to transform how people shop for the groceries they need from the retailers they trust, while creating flexible earning opportunities for shoppers. Through the Instacart Marketplace, Instacart Enterprise platform, and Instacart Ads ecosystem, the company powers ecommerce, fulfillment, in-store technology, AI offerings, and advertising for partners. With Instacart Health, the company is providing tools to increase nutrition security, make healthy choices easier for consumers, and expand the role that food can play in improving health outcomes. For more information, visit www.instacart.com/company.
- Private equity
- 25.2k employees
- Founded 2012
8
Databricks· San Francisco, California, United States
Databricks is the Data and AI company. More than 20,000 organizations worldwide — including adidas, AT&T, Bayer, Block, Mastercard, Rivian, Unilever, and over 60% of the Fortune 500 — rely on Databricks to build and scale data and AI apps, analytics and agents. Headquartered in San Francisco with 30+ offices around the globe, Databricks offers a unified Data Intelligence Platform that includes Agent Bricks, Lakeflow, Lakehouse, Lakebase and Unity Catalog. ---Databricks applicantsPlease apply through our official Careers page at databricks.com/company/careers. All official communication from Databricks will come from email addresses ending with @databricks.com or @goodtime.io (our meeting tool).
- Debt
- 16.4k employees
- Founded 2013
9
Autodesk· San Francisco, California, United States
Autodesk is changing how the world is designed and made. Our technology spans architecture, engineering, construction, product design, manufacturing, and media and entertainment. We empower innovators everywhere to solve challenges, big and small. From greener buildings to smarter products and more mesmerizing blockbusters, Autodesk software helps our customers design and make a better world for all.Over 100 million people use Autodesk software, like AutoCAD, Revit, Maya, 3ds Max, Fusion 360, SketchBook, and more, to unlock their creativity and solve important design, business, and environmental challenges. Our software runs on both personal computers and mobile devices. It taps the infinite computing power of the cloud to help teams around the world collaborate, design, simulate, and fabricate their ideas in 3D.We provide exceptional compensation and benefit packages, and we’d love for you to join us. We’re proud to be an equal opportunity employer, and we consider all qualified applicants without regard to race, gender, disability, veteran status, or other protected category. To see our culture in action, check out #AutodeskLife.We are headquartered in the San Francisco Bay Area and have over 10,000 employees worldwide.
- Post-IPO debt
- 15.4k employees
- Founded 1982
10
Twitch· San Francisco, California, United States
Twitch is where thousands of communities come together for whatever, every day. Together for streamers. Together for games we love. Together for each other.
- Series C
- 14.9k employees
- Founded 2011

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Find engineers at Data infrastructure companies in San Francisco

San Francisco has long been a hub for Data infrastructure, and the list above ranks the largest Data infrastructure companies headquartered there by current headcount, drawn from public LinkedIn and Crunchbase records. With 3,215 matching companies in Refolk’s index, this is a good map of where the Data infrastructure talent in San Francisco lives - useful whether you’re recruiting, partnering, or sizing a market.

The biggest Data infrastructure companies in San Francisco tend to be the gravitational centres for specialised talent - senior engineers, ML researchers, applied scientists, designers - while the smaller ones compete on speed, equity, and proximity to founders.

Refolk converts this list into a live search. Ask for “Data infrastructure engineers in San Francisco hiring senior staff” or “founders of Data infrastructure companies in San Francisco who left in the last 12 months” and Refolk returns a ranked shortlist with the evidence that earned each person a spot.

How this list is built

Refolk pulled Data infrastructure companies headquartered in San Francisco from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 10 employees. The list refreshes once a day.

Last refreshed: Wed, 05 Aug 2026 11:02:21 GMT

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The list draws on the public company graph - headcount and growth signals, funding history, and recency. The criteria chips at the top show exactly which filters produced it, and the methodology section explains the ranking.

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