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Top Biotech companies in San Francisco

Companies applying biology, chemistry, and computation to therapeutics and tooling. Filtered to companies headquartered in San Francisco.

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Built from a search like: “Top Biotech companies in San Francisco”

Ranked by current headcount across Biotech companies headquartered in San Francisco. Refreshed daily.

  1. 1
    Genentech· South San Francisco, California, United States
    • Series A
    • 18.2k employees
    • Founded 1976
  2. 2
    Liquid Trees· San Francisco, California, United States
    • Seed
    • 1.5k employees
    • Founded 2022
  3. 3
    Twist Bioscience· South San Francisco, California, United States
    • Post-IPO equity
    • 1.3k employees
    • Founded 2013
  4. 4
    Cytokinetics· South San Francisco, California, United States
    • Post-IPO equity
    • 771 employees
    • Founded 1998
  5. 5
    Veracyte, Inc.· South San Francisco, California, United States
    • Post-IPO equity
    • 707 employees
    • Founded 2008
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Find engineers at Biotech companies in San Francisco

San Francisco has long been a hub for Biotech, and the list above ranks the largest Biotech companies headquartered there by current headcount, drawn from public LinkedIn and Crunchbase records. With 293 matching companies in our index, this is a good map of where the Biotech talent in San Franciscolives - useful whether you’re recruiting, partnering, or sizing a market.

The biggest Biotech companies in San Francisco tend to be the gravitational centres for specialised talent - senior engineers, ML researchers, applied scientists, designers - while the smaller ones compete on speed, equity, and proximity to founders.

Refolk converts this list into a live search. Ask for “Biotech engineers in San Franciscohiring senior staff” or “founders of Biotech companies in San Franciscowho left in the last 12 months” and Refolk returns a ranked shortlist with the evidence that earned each person a spot.

How this list is built

Refolk pulled Biotech companies headquartered in San Francisco from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 10 employees. The list refreshes once a day.

Last refreshed: Sun, 21 Jun 2026 14:59:30 GMT

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