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Top Biotech companies in San Francisco

Companies applying biology, chemistry, and computation to therapeutics and tooling. Filtered to companies headquartered in San Francisco.

Built from a search like: Top Biotech companies in San Francisco

Ranked by current headcount across Biotech companies headquartered in San Francisco. Refreshed daily.

  1. 1
    Genentech· South San Francisco, California, United States

    About GenentechWe're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal.Making a difference in the lives of millions starts when you make a change in yours. If you’d like to join our team, view our openings at gene.com/careers. Our patient resource center is dedicated to getting patients and caregivers to the right resources. You can reach them at 1 (877) GENENTECH (436-3683)Monday-Friday, 6am-5pm PST or patientinfo@gene.com. Community Guidelines:1. We want to foster positive conversation around the issues we are passionate about. To that end, we remove profanity, content that contains threatening language, content that is aimed at private individuals, personal information, and repeated unwanted messages.2. Don’t mention any medicines by name — ours or anyone else’s.Because of the fair balance rules governing our industry, we cannot post any comments that reference any pharmaceutical brand, product, or service. Please do not mention any specific medicines by name, or include any links to third party sites in your comments.3. This isn’t the place to report or discuss side effects.This site is not intended as a forum for reporting side effects experienced while taking a Genentech product. Instead, you should report any side effects to Genentech Drug Safety at 1-888-835-2555. You can also report side effects of any prescription product directly to the FDA at 1-800-FDA-1088 or by visiting www.FDA.gov/medwatch.4. Don’t pitch your product or service.Please don't use our page as a place to promote your product or pitch your services. Please also avoid posting links to external sites. We reserve the right to remove any posts that are deemed promotional.

    • Series A
    • 18.3k employees
    • Founded 1976
  2. 2
    Liquid Trees· San Francisco, California, United States

    Say hello to Diatoms.Microscopic plants called Diatoms absorb 10-20 billion tonnes of carbon dioxide (CO2) every year. That's equal to the amount of carbon captured annually by all of the world's rainforests.Diatoms are considered the largest primary producers of oxygen on our planet. It is estimated that through photosynthesis, diatoms produce between 20% and 40% of the oxygen we breathe.With the campaign "Keeping the Planet cool with Diatoms" we are trying to raise awareness about Diatom potential in CO2 removal.We are in the process of removing 10GtCO2 by accelerating the growth of native diatoms in polluted open water systems.

    • Seed
    • 1.4k employees
    • Founded 2022
  3. 3
    Twist Bioscience· South San Francisco, California, United States

    Twist Bioscience is a synthetic biology company based in South San Francisco, California. The company has developed a proprietary silicon-based manufacturing process for the production of synthetic DNA. Twist Bioscience serves Life Science researchers who are changing the world for the better. Coming from diverse fields of medicine, agriculture, and industrial chemicals, scientists use our synthetic genes, oligo pools, biopharma services, and NGS target enrichment to better lives and improve the sustainability of the planet. Twist Bioscience is uniquely positioned to help accelerate these efforts by providing precision at a scale that is otherwise unavailable. Our technology overcomes inefficiencies and enables cost-effective, rapid, precise, high-throughput DNA synthesis and sequencing. We offer both the quality and quantity researchers need now to rapidly realize opportunities ahead. X @TwistBioscienceInstagram @twist_bioscienceYouTube youtube.com/TwistBioscience#WeMakeDNA

    • Post-IPO equity
    • 1.3k employees
    • Founded 2013
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  5. 4
    Cytokinetics· South San Francisco, California, United States

    Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.

    • Post-IPO equity
    • 792 employees
    • Founded 1998
  6. 5
    Veracyte, Inc.· South San Francisco, California, United States

    Veracyte is a global diagnostics company that empowers clinicians with the high-value insights they need to guide and assure patients at pivotal moments in the race to diagnose and treat cancer. Our growing menu of diagnostic tests answers important clinical questions to help patients avoid risky, costly procedures and interventions, and accelerate time to appropriate treatment.

    • Post-IPO equity
    • 733 employees
    • Founded 2008

Find engineers at Biotech companies in San Francisco

San Francisco has long been a hub for Biotech, and the list above ranks the largest Biotech companies headquartered there by current headcount, drawn from public LinkedIn and Crunchbase records. With 294 matching companies in Refolk’s index, this is a good map of where the Biotech talent in San Francisco lives - useful whether you’re recruiting, partnering, or sizing a market.

The biggest Biotech companies in San Francisco tend to be the gravitational centres for specialised talent - senior engineers, ML researchers, applied scientists, designers - while the smaller ones compete on speed, equity, and proximity to founders.

Refolk converts this list into a live search. Ask for Biotech engineers in San Francisco hiring senior staff” or “founders of Biotech companies in San Francisco who left in the last 12 months” and Refolk returns a ranked shortlist with the evidence that earned each person a spot.

How this list is built

Refolk pulled Biotech companies headquartered in San Francisco from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 10 employees. The list refreshes once a day.

Last refreshed: Wed, 05 Aug 2026 20:34:01 GMT

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How is this ranking built?

The list draws on the public company graph - headcount and growth signals, funding history, and recency. The criteria chips at the top show exactly which filters produced it, and the methodology section explains the ranking.

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The underlying index updates continuously and this page re-renders at least daily. Last refreshed: Wed, 05 Aug 2026 20:34:01 GMT.

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