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Top Blockchain companies in San Francisco

Companies building L1s, L2s, wallets, infra, and apps on public blockchains. Filtered to companies headquartered in San Francisco.

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Built from a search like: “Top Blockchain companies in San Francisco”

Ranked by current headcount across Blockchain companies headquartered in San Francisco. Refreshed daily.

  1. 1
    Wells Fargo· San Francisco, California, United States
    • 224.7k employees
  2. 2
    Union Bank· San Francisco, California, United States
    • 8.2k employees
  3. 3
    SoFi· San Francisco, California, United States
    • Post-IPO equity
    • 6.7k employees
    • Founded 2011
  4. 4
    Delta Dental Ins.· San Francisco, California, United States
    • 6k employees
    • Founded 1955
  5. 5
    Toko· San Francisco, California, United States
    • 5k employees
    • Founded 2017
Reveal 1,155 more·100 free credits, no card

Find engineers at Blockchain companies in San Francisco

San Francisco has long been a hub for Blockchain, and the list above ranks the largest Blockchain companies headquartered there by current headcount, drawn from public LinkedIn and Crunchbase records. With 1,160 matching companies in our index, this is a good map of where the Blockchain talent in San Franciscolives - useful whether you’re recruiting, partnering, or sizing a market.

The biggest Blockchain companies in San Francisco tend to be the gravitational centres for specialised talent - senior engineers, ML researchers, applied scientists, designers - while the smaller ones compete on speed, equity, and proximity to founders.

Refolk converts this list into a live search. Ask for “Blockchain engineers in San Franciscohiring senior staff” or “founders of Blockchain companies in San Franciscowho left in the last 12 months” and Refolk returns a ranked shortlist with the evidence that earned each person a spot.

How this list is built

Refolk pulled Blockchain companies headquartered in San Francisco from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 10 employees. The list refreshes once a day.

Last refreshed: Sun, 21 Jun 2026 09:24:46 GMT

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