Top Python Data science repositories on GitHub
Notebooks, analysis libraries, and data tooling. Filtered to projects whose primary language is Python.
Ranked by stars across 1,180 Python repositories tagged data-science. Refreshed daily.
- 1scikit-learn/scikit-learn★ 66,378 · ⑂ 27,087
scikit-learn: machine learning in Python
- machine-learning
- python
- statistics
- data-science
- data-analysis
- 2Asabeneh/30-Days-Of-Python★ 65,671 · ⑂ 12,291
The 30 Days of Python programming challenge is a step-by-step guide to learn the Python programming language in 30 days. This challenge may take more than 100 days. Follow your own pace. These videos may help too: https://www.youtube.com/channel/UC7PNRuno1rzYPb1xLa4yktw
- 30-days-of-python
- python
- flask
- github
- heroku
- matplotlib
- 3keras-team/keras★ 64,094 · ⑂ 19,736
Deep Learning for humans
- deep-learning
- tensorflow
- neural-networks
- machine-learning
- data-science
- python
- 4pandas-dev/pandas★ 49,034 · ⑂ 20,019
Flexible and powerful data analysis / manipulation library for Python, providing labeled data structures similar to R data.frame objects, statistical functions, and much more
- data-analysis
- pandas
- flexible
- alignment
- python
- data-science
- 5apache/airflow★ 45,884 · ⑂ 17,264
Apache Airflow - A platform to programmatically author, schedule, and monitor workflows
- airflow
- apache
- apache-airflow
- python
- scheduler
- workflow
- 6streamlit/streamlit★ 45,020 · ⑂ 4,291
Streamlit — A faster way to build and share data apps.
- python
- machine-learning
- data-science
- deep-learning
- data-visualization
- streamlit
- 7SimplifyJobs/Summer2026-Internships★ 44,982 · ⑂ 3,180
Summer 2026 software engineering, data science, AI, quant, product management, and hardware internship postings. Updated daily by Simplify and Pitt CSC.
- interview-preparation
- internships
- jobs
- university
- fall-2026
- github
- 8gradio-app/gradio★ 42,970 · ⑂ 3,506
Build and share delightful machine learning apps, all in Python. 🌟 Star to support our work!
- machine-learning
- models
- ui
- ui-components
- interface
- python
- 9ray-project/ray★ 42,953 · ⑂ 7,710
Ray is an AI compute engine. Ray consists of a core distributed runtime and a set of AI Libraries for accelerating ML workloads.
- ray
- distributed
- parallel
- machine-learning
- reinforcement-learning
- deep-learning
- 10explosion/spaCy★ 33,675 · ⑂ 4,688
💫 Industrial-strength Natural Language Processing (NLP) in Python
- natural-language-processing
- data-science
- machine-learning
- python
- cython
- nlp
- 11eriklindernoren/ML-From-Scratch★ 31,944 · ⑂ 5,347
Machine Learning From Scratch. Bare bones NumPy implementations of machine learning models and algorithms with a focus on accessibility. Aims to cover everything from linear regression to deep learning.
- machine-learning
- deep-learning
- deep-reinforcement-learning
- machine-learning-from-scratch
- data-science
- data-mining
- 12Lightning-AI/pytorch-lightning★ 31,198 · ⑂ 3,742
Pretrain, finetune ANY AI model of ANY size on 1 or 10,000+ GPUs with zero code changes.
- python
- deep-learning
- artificial-intelligence
- ai
- pytorch
- data-science
- 13donnemartin/data-science-ipython-notebooks★ 29,177 · ⑂ 8,025
Data science Python notebooks: Deep learning (TensorFlow, Theano, Caffe, Keras), scikit-learn, Kaggle, big data (Spark, Hadoop MapReduce, HDFS), matplotlib, pandas, NumPy, SciPy, Python essentials, AWS, and various command lines.
- python
- machine-learning
- deep-learning
- data-science
- big-data
- aws
- 14d2l-ai/d2l-en★ 29,023 · ⑂ 5,074
Interactive deep learning book with multi-framework code, math, and discussions. Adopted at 500 universities from 70 countries including Stanford, MIT, Harvard, and Cambridge.
- deep-learning
- machine-learning
- book
- notebook
- computer-vision
- natural-language-processing
- 15reflex-dev/reflex★ 28,579 · ⑂ 1,742
🕸️ Web apps in pure Python 🐍
- python
- framework
- open-source
- gui
- dashboard
- fullstack
- 16plotly/dash★ 24,267 · ⑂ 2,299
Data Apps & Dashboards for Python. No JavaScript Required.
- dash
- plotly
- data-visualization
- data-science
- gui-framework
- flask
- 17sinaptik-ai/pandas-ai★ 23,591 · ⑂ 2,327
Chat with your database or your datalake (SQL, CSV, parquet). PandasAI makes data analysis conversational using LLMs and RAG.
- llm
- pandas
- ai
- data-analysis
- data-science
- gpt-4
- 18matplotlib/matplotlib★ 22,909 · ⑂ 8,359
matplotlib: plotting with Python
- matplotlib
- data-visualization
- data-science
- python
- qt
- wx
- 19PrefectHQ/prefect★ 22,655 · ⑂ 2,346
Prefect is a workflow orchestration framework for building resilient data pipelines in Python.
- python
- workflow
- data-engineering
- data-science
- workflow-engine
- prefect
- 20recommenders-team/recommenders★ 21,778 · ⑂ 3,326
Best Practices on Recommendation Systems
- machine-learning
- recommender
- ranking
- deep-learning
- python
- jupyter-notebook
- 21marimo-team/marimo★ 21,529 · ⑂ 1,144
A reactive notebook for Python — run reproducible experiments, query with SQL, execute as a script, deploy as an app, and version with git. Stored as pure Python. All in a modern, AI-native editor.
- notebooks
- python
- data-science
- machine-learning
- artificial-intelligence
- data-visualization
- 22akfamily/akshare★ 20,546 · ⑂ 3,292
AKShare is an elegant and simple financial data interface library for Python, built for human beings! 开源财经数据接口库
- futures
- financial-data
- data-science
- quant
- fundamental
- akshare
- 23ipython/ipython★ 16,724 · ⑂ 4,487
Official repository for IPython itself. Other repos in the IPython organization contain things like the website, documentation builds, etc.
- ipython
- jupyter
- data-science
- notebook
- python
- repl
- 24piskvorky/gensim★ 16,443 · ⑂ 4,408
Topic Modelling for Humans
- gensim
- topic-modeling
- information-retrieval
- machine-learning
- natural-language-processing
- nlp
- 25dagster-io/dagster★ 15,728 · ⑂ 2,166
An orchestration platform for the development, production, and observation of data assets.
- data-pipelines
- dagster
- workflow
- data-science
- workflow-automation
- python
Find Python engineers shipping Data science
The list above ranks the most-starred public Python repositories tagged with the Data science topic, drawn from the public GitHub graph. Across 1,180 matching repositories, the contributors are a tight cluster of engineers with both Python chops and real Data science experience.
That overlap is rare. Most Python engineers haven’t shipped Data science, and most Data science maintainers don’t write Python. The people on this list’s contributor graph are the ones who do both.
Refolk turns this list into a search. Ask for “Python Data science maintainers hiring” or “Python engineers shipping Data science in 2025” and Refolk returns a ranked shortlist with the commits, profiles, and projects behind each name.
How this list is built
Last refreshed: Sun, 21 Jun 2026 11:20:45 GMT
Need a more specific search?
Refolk runs natural-language searches across GitHub, LinkedIn, and the open web. Try one of these:
Related lists
- Python · Machine learning
- Python · Deep learning
- Python · Computer vision
- Python · Natural language processing
- Python · LLM
- Python · AI agents
- Python · RAG
- Python · Embeddings
See all repository lists.