Top Python LLM repositories on GitHub
Large language model frameworks, agents, runtimes, and inference servers. Filtered to projects whose primary language is Python.
Ranked by stars across 3,534 Python repositories tagged llm. Refreshed daily.
- 1Significant-Gravitas/AutoGPT★ 184,042 · ⑂ 46,246
AutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.
- ai
- openai
- python
- artificial-intelligence
- autonomous-agents
- llama-api
- 2huggingface/transformers★ 160,327 · ⑂ 33,126
🤗 Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.
- nlp
- natural-language-processing
- pytorch
- pytorch-transformers
- transformer
- model-hub
- 3NousResearch/hermes-agent★ 136,326 · ⑂ 20,901
The agent that grows with you
- ai
- ai-agent
- ai-agents
- llm
- anthropic
- chatgpt
- 4langchain-ai/langchain★ 135,982 · ⑂ 22,480
The agent engineering platform. Available in TypeScript!
- ai
- anthropic
- gemini
- langchain
- llm
- openai
- 5open-webui/open-webui★ 135,830 · ⑂ 19,340
User-friendly AI Interface (Supports Ollama, OpenAI API, ...)
- ollama
- ollama-webui
- llm
- webui
- self-hosted
- llm-ui
- 6browser-use/browser-use★ 92,581 · ⑂ 10,492
🌐 Make websites accessible for AI agents. Automate tasks online with ease.
- llm
- ai-agents
- ai-tools
- browser-automation
- python
- browser-use
- 7vllm-project/vllm★ 79,230 · ⑂ 16,497
A high-throughput and memory-efficient inference and serving engine for LLMs
- gpt
- llm
- pytorch
- model-serving
- transformer
- llm-serving
- 8OpenHands/OpenHands★ 72,775 · ⑂ 9,215
🙌 OpenHands: AI-Driven Development
- agent
- artificial-intelligence
- llm
- chatgpt
- claude-ai
- cli
- 9hiyouga/LlamaFactory★ 70,990 · ⑂ 8,673
Unified Efficient Fine-Tuning of 100+ LLMs & VLMs (ACL 2024)
- fine-tuning
- llama
- llm
- peft
- transformers
- rlhf
- 10TauricResearch/TradingAgents★ 70,530 · ⑂ 13,622
TradingAgents: Multi-Agents LLM Financial Trading Framework
- agent
- finance
- llm
- multiagent
- trading
- 11FoundationAgents/MetaGPT★ 67,741 · ⑂ 8,617
🌟 The Multi-Agent Framework: First AI Software Company, Towards Natural Language Programming
- agent
- gpt
- llm
- metagpt
- multi-agent
- 12bytedance/deer-flow★ 65,665 · ⑂ 8,681
An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.
- agent
- agentic
- agentic-framework
- agentic-workflow
- ai
- ai-agents
- 13unslothai/unsloth★ 63,724 · ⑂ 5,615
Web UI for training and running open models like Gemma 4, Qwen3.6, DeepSeek, gpt-oss locally.
- fine-tuning
- llama
- llms
- mistral
- gemma
- llama3
- 14sansan0/TrendRadar★ 56,864 · ⑂ 24,131
⭐AI-driven public opinion & trend monitor with multi-platform aggregation, RSS, and smart alerts.🎯 告别信息过载,你的 AI 舆情监控助手与热点筛选工具!聚合多平台热点 + RSS 订阅,支持关键词精准筛选。AI 智能筛选新闻 + AI 翻译 + AI 分析简报直推手机,也支持接入 MCP 架构,赋能 AI 自然语言对话分析、情感洞察与趋势预测等。支持 Docker ,数据本地/云端自持。集成微信/飞书/钉钉/Telegram/邮件/ntfy/bark/slack 等渠道智能推送。
- data-analysis
- python
- trending-topics
- news
- hot-news
- docker
- 15JuliusBrussee/caveman★ 55,498 · ⑂ 3,041
🪨 why use many token when few token do trick — Claude Code skill that cuts 65% of tokens by talking like caveman
- ai
- anthropic
- caveman
- claude
- claude-code
- llm
- 16
- 17MemPalace/mempalace★ 51,376 · ⑂ 6,761
The best-benchmarked open-source AI memory system. And it's free.
- ai
- chromadb
- llm
- mcp
- memory
- python
- 18run-llama/llama_index★ 49,181 · ⑂ 7,365
LlamaIndex is the leading document agent and OCR platform
- agents
- application
- data
- fine-tuning
- framework
- llamaindex
- 19BerriAI/litellm★ 45,962 · ⑂ 7,821
Python SDK, Proxy Server (AI Gateway) to call 100+ LLM APIs in OpenAI (or native) format, with cost tracking, guardrails, loadbalancing and logging. [Bedrock, Azure, OpenAI, VertexAI, Cohere, Anthropic, Sagemaker, HuggingFace, VLLM, NVIDIA NIM]
- anthropic
- langchain
- llm
- llmops
- openai
- ai-gateway
- 20zhayujie/CowAgent★ 44,098 · ⑂ 10,060
CowAgent (chatgpt-on-wechat) 是基于大模型的超级AI助理,能主动思考和任务规划、访问操作系统和外部资源、创造和执行Skills、通过长期记忆和知识库不断成长,比OpenClaw更轻量和便捷。同时支持微信、飞书、钉钉、企微、QQ、公众号、网页等接入,可选择DeepSeek/OpenAI/Claude/Gemini/ MiniMax/Qwen/GLM/LinkAI,能处理文本、语音、图片和文件,可快速搭建个人AI助理和企业数字员工。
- openai
- python3
- feishu-bot
- linkai
- ai
- 21
- 22hesreallyhim/awesome-claude-code★ 42,788 · ⑂ 3,628
A curated list of awesome skills, hooks, slash-commands, agent orchestrators, applications, and plugins for Claude Code by Anthropic
- anthropic
- anthropic-claude
- awesome
- awesome-list
- awesome-lists
- awesome-resources
- 23ray-project/ray★ 42,442 · ⑂ 7,531
Ray is an AI compute engine. Ray consists of a core distributed runtime and a set of AI Libraries for accelerating ML workloads.
- ray
- distributed
- parallel
- machine-learning
- reinforcement-learning
- deep-learning
- 24HKUDS/nanobot★ 41,834 · ⑂ 7,354
"🐈 nanobot: The Ultra-Lightweight Personal AI Agent"
- ai
- ai-agent
- ai-agents
- anthropic
- chatgpt
- claude
- 252noise/ChatTTS★ 39,217 · ⑂ 4,249
A generative speech model for daily dialogue.
- agent
- text-to-speech
- chat
- chatgpt
- chattts
- chinese
Find Python engineers shipping LLM
The list above ranks the most-starred public Python repositories tagged with the LLM topic, drawn from the public GitHub graph. Across 3,534 matching repositories, the contributors are a tight cluster of engineers with both Python chops and real LLM experience.
That overlap is rare. Most Python engineers haven’t shipped LLM, and most LLM maintainers don’t write Python. The people on this list’s contributor graph are the ones who do both.
Refolk turns this list into a search. Ask for “Python LLM maintainers hiring” or “Python engineers shipping LLM in 2025” and Refolk returns a ranked shortlist with the commits, profiles, and projects behind each name.
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Last refreshed: Thu, 07 May 2026 05:54:14 GMT
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