Refolk

Top Python LLM repositories on GitHub

Large language model frameworks, agents, runtimes, and inference servers. Filtered to projects whose primary language is Python.

Ranked by stars across 3,875 Python repositories tagged llm. Refreshed daily.

  1. 1
    NousResearch/hermes-agent198,482 · ⑂ 35,218

    The agent that grows with you

    • ai
    • ai-agent
    • ai-agents
    • llm
    • anthropic
    • chatgpt
  2. 2
    Significant-Gravitas/AutoGPT185,046 · ⑂ 46,125

    AutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.

    • ai
    • openai
    • python
    • artificial-intelligence
    • autonomous-agents
    • llama-api
  3. 3
    huggingface/transformers161,762 · ⑂ 33,563

    🤗 Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.

    • nlp
    • natural-language-processing
    • pytorch
    • pytorch-transformers
    • transformer
    • model-hub
  4. 4
    open-webui/open-webui142,457 · ⑂ 20,485

    User-friendly AI Interface (Supports Ollama, OpenAI API, ...)

    • ollama
    • ollama-webui
    • llm
    • webui
    • self-hosted
    • llm-ui
  5. 5
    langchain-ai/langchain139,781 · ⑂ 23,183

    The agent engineering platform.

    • ai
    • anthropic
    • gemini
    • langchain
    • llm
    • openai
  6. 6
    browser-use/browser-use99,786 · ⑂ 11,127

    🌐 Make websites accessible for AI agents. Automate tasks online with ease.

    • llm
    • ai-agents
    • ai-tools
    • browser-automation
    • python
    • browser-use
  7. 7
    TauricResearch/TradingAgents87,684 · ⑂ 16,933

    TradingAgents: Multi-Agents LLM Financial Trading Framework

    • agent
    • finance
    • llm
    • multiagent
    • trading
  8. 8
    vllm-project/vllm83,440 · ⑂ 18,275

    A high-throughput and memory-efficient inference and serving engine for LLMs

    • gpt
    • llm
    • pytorch
    • model-serving
    • transformer
    • llm-serving
  9. 9
    OpenHands/OpenHands77,875 · ⑂ 9,900

    🙌 OpenHands: AI-Driven Development

    • agent
    • artificial-intelligence
    • llm
    • chatgpt
    • claude-ai
    • cli
  10. 10
    hiyouga/LlamaFactory72,315 · ⑂ 8,849

    Unified Efficient Fine-Tuning of 100+ LLMs & VLMs (ACL 2024)

    • fine-tuning
    • llama
    • llm
    • peft
    • transformers
    • rlhf
  11. 11
    bytedance/deer-flow72,134 · ⑂ 9,788

    An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.

    • agent
    • agentic
    • agentic-framework
    • agentic-workflow
    • ai
    • ai-agents
  12. 12
    FoundationAgents/MetaGPT68,934 · ⑂ 8,806

    🌟 The Multi-Agent Framework: First AI Software Company, Towards Natural Language Programming

    • agent
    • gpt
    • llm
    • metagpt
    • multi-agent
  13. 13
    shareAI-lab/learn-claude-code67,605 · ⑂ 10,999

    Bash is all you need - A nano claude code–like 「agent harness」, built from 0 to 1

    • agent
    • claude-code
    • teaching
    • agent-development
    • ai-agent
    • claude
  14. 14
    unslothai/unsloth66,993 · ⑂ 6,018

    Unsloth Studio is a web UI for training and running open models like Gemma 4, Qwen3.6, DeepSeek, gpt-oss locally.

    • fine-tuning
    • llama
    • llms
    • mistral
    • gemma
    • llama3
  15. 15
    datawhalechina/hello-agents60,593 · ⑂ 7,467

    📚 《从零开始构建智能体》——从零开始的智能体原理与实践教程

    • agent
    • tutorial
    • llm
    • rag
  16. 16
    sansan0/TrendRadar59,712 · ⑂ 24,692

    ⭐AI-driven public opinion & trend monitor with multi-platform aggregation, RSS, and smart alerts.🎯 告别信息过载,你的 AI 舆情监控助手与热点筛选工具!聚合多平台热点 + RSS 订阅,支持关键词精准筛选。AI 智能筛选新闻 + AI 翻译 + AI 分析简报直推手机,也支持接入 MCP 架构,赋能 AI 自然语言对话分析、情感洞察与趋势预测等。支持 Docker ,数据本地/云端自持。集成微信/飞书/钉钉/Telegram/邮件/ntfy/bark/slack 等渠道智能推送。

    • data-analysis
    • python
    • trending-topics
    • news
    • hot-news
    • docker
  17. 17
    mem0ai/mem059,006 · ⑂ 6,808

    Universal memory layer for AI Agents

    • ai
    • chatgpt
    • llm
    • python
    • chatbots
    • rag
  18. 18
    MemPalace/mempalace56,077 · ⑂ 7,261

    The best-benchmarked open-source AI memory system. And it's free.

    • ai
    • chromadb
    • llm
    • mcp
    • memory
    • python
  19. 19
    BerriAI/litellm51,010 · ⑂ 9,031

    Python SDK, Proxy Server (AI Gateway) to call 100+ LLM APIs in OpenAI (or native) format, with cost tracking, guardrails, loadbalancing and logging. [Bedrock, Azure, OpenAI, VertexAI, Cohere, Anthropic, Sagemaker, HuggingFace, VLLM, NVIDIA NIM]

    • anthropic
    • langchain
    • llm
    • llmops
    • openai
    • ai-gateway
  20. 20
    run-llama/llama_index50,246 · ⑂ 7,597

    LlamaIndex is the leading document agent and OCR platform

    • agents
    • application
    • data
    • fine-tuning
    • framework
    • llamaindex
  21. 21
    hesreallyhim/awesome-claude-code46,944 · ⑂ 4,096

    A curated list of awesome skills, hooks, slash-commands, agent orchestrators, applications, and plugins for Claude Code by Anthropic

    • anthropic
    • anthropic-claude
    • awesome
    • awesome-list
    • awesome-lists
    • awesome-resources
  22. 22
    zhayujie/CowAgent45,501 · ⑂ 10,223

    Open-source super AI assistant & Agent Harness. Plans tasks, runs tools and skills, self-evolves with memory and knowledge. Multi-model, multi-channel. Lightweight, extensible, one-line install. (formerly chatgpt-on-wechat)

    • openai
    • ai
    • llm
    • ai-agent
    • deepseek
    • mcp
  23. 23
    HKUDS/nanobot44,495 · ⑂ 7,860

    Lightweight, open-source AI agent for your tools, chats, and workflows.

    • ai
    • ai-agent
    • ai-agents
    • anthropic
    • chatgpt
    • claude
  24. 24
    ZhuLinsen/daily_stock_analysis43,699 · ⑂ 41,148

    LLM 驱动的多市场股票智能分析系统:多源行情、实时新闻、决策看板与自动推送,支持零成本定时运行。 LLM-powered multi-market stock analysis system with multi-source market data, real-time news, decision dashboard, automated notifications, and cost-free scheduled runs.

    • aigc
    • llm
    • quant
    • quantitative-trading
    • a-stock
    • ai-agent
  25. 25
    ray-project/ray42,947 · ⑂ 7,707

    Ray is an AI compute engine. Ray consists of a core distributed runtime and a set of AI Libraries for accelerating ML workloads.

    • ray
    • distributed
    • parallel
    • machine-learning
    • reinforcement-learning
    • deep-learning

Find Python engineers shipping LLM

The list above ranks the most-starred public Python repositories tagged with the LLM topic, drawn from the public GitHub graph. Across 3,875 matching repositories, the contributors are a tight cluster of engineers with both Python chops and real LLM experience.

That overlap is rare. Most Python engineers haven’t shipped LLM, and most LLM maintainers don’t write Python. The people on this list’s contributor graph are the ones who do both.

Refolk turns this list into a search. Ask for Python LLM maintainers hiring” or Python engineers shipping LLM in 2025” and Refolk returns a ranked shortlist with the commits, profiles, and projects behind each name.

How this list is built

Refolk searched GitHub for public Python repositories tagged with the LLM topic, ranked them by stargazer count, and kept those with at least 25 stars. The list refreshes once a day.

Last refreshed: Sun, 21 Jun 2026 07:07:27 GMT

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