Top Python AI agents repositories on GitHub

Autonomous and tool-using agent frameworks built around LLMs. Filtered to projects whose primary language is Python.

Ranked by stars across 2,000 Python repositories tagged ai-agents. Refreshed daily.

1
NousResearch/hermes-agent★ 251,423 · ⑂ 53,993
The agent that grows with you
- ai
- ai-agent
- ai-agents
- llm
- anthropic
- chatgpt
2
langchain-ai/langchain★ 147,474 · ⑂ 24,708
The agent engineering platform.
- ai
- anthropic
- gemini
- langchain
- llm
- openai
3
Graphify-Labs/graphify★ 124,045 · ⑂ 11,972
Turn any codebase, with its docs, SQL schemas, configs, and PDFs, into a queryable knowledge graph. A /graphify skill for Claude Code, Cursor, Codex, and Gemini CLI: local deterministic AST parsing, every edge explained, no vector store.
- claude-code
- graphrag
- knowledge-graph
- codex
- openclaw
- skills
4
browser-use/browser-use★ 117,205 · ⑂ 12,938
Agents that use the browser.
- llm
- ai-agents
- ai-tools
- browser-automation
- python
- browser-use
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5
unclecode/crawl4ai★ 84,791 · ⑂ 8,780
Open-source web crawler and scraper for LLMs and AI agents: any website into clean, LLM-ready Markdown. Run it yourself, or use Crawl4AI Cloud with one key.
- ai
- ai-agents
- crawler
- data-extraction
- llm
- markdown
6
bytedance/deer-flow★ 83,411 · ⑂ 11,589
An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.
- agent
- agentic
- agentic-framework
- agentic-workflow
- ai
- ai-agents
7
ComposioHQ/awesome-claude-skills★ 76,549 · ⑂ 8,960
A curated list of awesome Claude Skills, resources, and tools for customizing Claude AI workflows
- claude
- claude-code
- agent-skills
- ai-agents
- antigravity
- automation
8
asgeirtj/system_prompts_leaks★ 68,969 · ⑂ 11,204
Documented system prompts from Anthropic - Claude Fable 5.1, Opus 5.5, Claude Design, Claude Code. OpenAI - ChatGPT GPT-6-Astra, Codex. Google - Gemini 3.8 Flash, 3.1 Pro, Antigravity. xAI - Grok, Grok Bot, Cursor, Kimi and more! Updated regularly.
- ai
- anthropic
- chatbot
- chatgpt
- claude
- claude-code
9
mem0ai/mem0★ 66,609 · ⑂ 7,851
The Memory Layer for AI Agents - Drop-in memory infrastructure for AI agents and apps. Context that persists. Built for production.
- ai
- chatgpt
- llm
- python
- rag
- long-term-memory
10
rohitg00/ai-engineering-from-scratch★ 64,721 · ⑂ 11,131
Learn it. Build it. Ship it for others.
- agents
- ai
- ai-agents
- ai-engineering
- computer-vision
- course
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11
crewAIInc/crewAI★ 59,374 · ⑂ 8,652
Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.
- agents
- ai
- ai-agents
- llms
- aiagentframework
12
HKUDS/nanobot★ 48,805 · ⑂ 8,609
Ultra-lightweight, open-source, self-hosted personal AI agent framework in Python with WebUI, tools, memory, MCP, multi-agent workflows, automation, and chat apps
- ai-agent
- ai-agents
- openclaw
- agent-framework
- chatbot
- chatops
13
sickn33/agentic-awesome-skills★ 47,277 · ⑂ 6,887
AAS Core is the local, agent-first control plane for complete catalog discovery, agent-owned selection, stack validation, and planning, backed by 2,400+ agentic skills. Includes CLI, local MCP, catalog, plugins, and Workbench.
- agentic-skills
- ai-agents
- antigravity
- claude-code
- mcp
- ai-workflows
14
zhayujie/CowAgent★ 47,228 · ⑂ 10,375
Open-source personal AI assistant & Agent Harness. Plans tasks, runs tools and skills, self-evolves with memory and knowledge. Multi-agent, multi-model, multi-channel. Lightweight, extensible, one-line install.
- openai
- ai
- llm
- ai-agent
- deepseek
- mcp
15
MadsLorentzen/ai-job-search★ 45,040 · ⑂ 15,621
The job search that runs on your machine. AI job application framework built on Claude Code: evaluate postings, tailor CVs, write cover letters, prep interviews. Fork it and own it.
- ai
- ai-agents
- career
- claude-code
- cover-letter
- cv
16
langchain-ai/langgraph★ 42,744 · ⑂ 7,267
Build resilient agents.
- agents
- ai
- ai-agents
- chatgpt
- deepagents
- enterprise
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17
agno-agi/agno★ 42,567 · ⑂ 6,100
Build, run, and manage agent platforms.
- developer-tools
- python
- agents
- ai
- ai-agents
18
HKUDS/DeepTutor★ 40,821 · ⑂ 5,154
DeepTutor: Lifelong Personalized Tutoring. https://deeptutor.info/.
- ai-tutor
- deepresearch
- interactive-learning
- multi-agent-systems
- rag
- ai-agents
19
wshobson/agents★ 40,218 · ⑂ 4,287
Multi-harness agentic plugin marketplace for Claude Code, Codex, Cursor, OpenCode, GitHub Copilot, Google Antigravity, and Pi
- anthropic
- agent-skills
- agentic-ai
- ai-agents
- cursor
- cursor-rules

20
VectifyAI/PageIndex★ 38,688 · ⑂ 3,351
📑 PageIndex: Document Index for Vectorless, Reasoning-based RAG
- agentic-ai
- agents
- ai
- ai-agents
- context-engineering
- llm
21
ashishpatel26/500-AI-Agents-Projects★ 38,326 · ⑂ 6,859
The 500 AI Agents Projects is a curated collection of AI agent use cases across various industries. It showcases practical applications and provides links to open-source projects for implementation, illustrating how AI agents are transforming sectors such as healthcare, finance, education, retail, and more.
- ai-agents
- genai
22
virgiliojr94/book-to-skill★ 33,840 · ⑂ 3,539
Turn any technical book PDF into a Claude Code skill — ready to study, reference, and use while you work.
- agent-skills
- ai-agents
- context-engineering
- document-processing
- edtech
- knowledge-base
23
mukul975/Anthropic-Cybersecurity-Skills★ 33,813 · ⑂ 4,104
817 structured cybersecurity skills for AI agents · Mapped to 6 frameworks: MITRE ATT&CK, NIST CSF 2.0, MITRE ATLAS, D3FEND, NIST AI RMF & MITRE F3 (Fight Fraud) · agentskills.io standard · Works with Claude Code, GitHub Copilot, Codex CLI, Cursor, Gemini CLI & 20+ platforms · 29 security domains · Apache 2.0
- ai-agents
- claude-code
- cybersecurity
- incident-response
- mitre-attack
- penetration-testing
24
CloakHQ/CloakBrowser★ 31,912 · ⑂ 2,650
Stealth Chromium that passes every bot detection test. Drop-in Playwright replacement with source-level fingerprint patches. 30/30 tests passed.
- anti-detect
- bot-detection
- browser-automation
- chromium
- cloudflare
- fingerprint
25
topoteretes/cognee★ 31,400 · ⑂ 3,212
Cognee is the open-source AI memory platform for agents. Give your AI agents persistent long-term memory with small models for free
- ai
- cognitive-architecture
- vector-database
- ai-agents
- graph-database
- ai-memory

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Find Python engineers shipping AI agents

The list above ranks the most-starred public Python repositories tagged with the AI agents topic, drawn from the public GitHub graph. Across 2,000 matching repositories, the contributors are a tight cluster of engineers with both Python chops and real AI agents experience.

That overlap is rare. Most Python engineers haven’t shipped AI agents, and most AI agents maintainers don’t write Python. The people on this list’s contributor graph are the ones who do both.

Refolk turns this list into a search. Ask for “Python AI agents maintainers hiring” or “Python engineers shipping AI agents in 2025” and Refolk returns a ranked shortlist with the commits, profiles, and projects behind each name.

How this list is built

Refolk searched GitHub for public Python repositories tagged with the AI agents topic, ranked them by stargazer count, and kept those with at least 25 stars. The list refreshes once a day.

Last refreshed: Mon, 05 Oct 2026 21:38:59 GMT

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