Top Python AI agents repositories on GitHub

Autonomous and tool-using agent frameworks built around LLMs. Filtered to projects whose primary language is Python.

Ranked by stars across 1,846 Python repositories tagged ai-agents. Refreshed daily.

1
NousResearch/hermes-agent★ 247,377 · ⑂ 52,012
The agent that grows with you
- ai
- ai-agent
- ai-agents
- llm
- anthropic
- chatgpt
2
langchain-ai/langchain★ 146,725 · ⑂ 24,536
The agent engineering platform.
- ai
- anthropic
- gemini
- langchain
- llm
- openai
3
Graphify-Labs/graphify★ 119,789 · ⑂ 11,579
Turn any codebase, with its docs, SQL schemas, configs, and PDFs, into a queryable knowledge graph. A /graphify skill for Claude Code, Cursor, Codex, and Gemini CLI: local deterministic AST parsing, every edge explained, no vector store.
- claude-code
- graphrag
- knowledge-graph
- codex
- openclaw
- skills
4
browser-use/browser-use★ 115,481 · ⑂ 12,708
Agents that use the browser.
- llm
- ai-agents
- ai-tools
- browser-automation
- python
- browser-use
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5
bytedance/deer-flow★ 82,746 · ⑂ 11,431
An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.
- agent
- agentic
- agentic-framework
- agentic-workflow
- ai
- ai-agents
6
ComposioHQ/awesome-claude-skills★ 75,380 · ⑂ 8,735
A curated list of awesome Claude Skills, resources, and tools for customizing Claude AI workflows
- claude
- claude-code
- agent-skills
- ai-agents
- antigravity
- automation
7
mem0ai/mem0★ 65,706 · ⑂ 7,715
The Memory Layer for AI Agents - Drop-in memory infrastructure for AI agents and apps. Context that persists. Built for production.
- ai
- chatgpt
- llm
- python
- rag
- long-term-memory
8
crewAIInc/crewAI★ 58,811 · ⑂ 8,521
Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.
- agents
- ai
- ai-agents
- llms
- aiagentframework
9
rohitg00/ai-engineering-from-scratch★ 55,074 · ⑂ 9,689
Learn it. Build it. Ship it for others.
- agents
- ai
- ai-agents
- ai-engineering
- computer-vision
- course
10
HKUDS/nanobot★ 48,400 · ⑂ 8,556
Ultra-lightweight, open-source, self-hosted personal AI agent framework in Python with WebUI, tools, memory, MCP, multi-agent workflows, automation, and chat apps
- ai-agent
- ai-agents
- openclaw
- agent-framework
- chatbot
- chatops
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11
zhayujie/CowAgent★ 47,051 · ⑂ 10,365
Open-source super AI assistant & Agent Harness. Plans tasks, runs tools and skills, self-evolves with memory and knowledge. Multi-agent, multi-model, multi-channel. Lightweight, extensible, one-line install. (formerly chatgpt-on-wechat)
- openai
- ai
- llm
- ai-agent
- deepseek
- mcp
12
sickn33/agentic-awesome-skills★ 46,633 · ⑂ 6,803
AAS Core is the local, agent-first control plane for complete catalog discovery, agent-owned selection, stack validation, and planning, backed by 2,400+ agentic skills. Includes CLI, local MCP, catalog, plugins, and Workbench.
- agentic-skills
- ai-agents
- antigravity
- claude-code
- mcp
- ai-workflows
13
MadsLorentzen/ai-job-search★ 43,436 · ⑂ 14,915
The job search that runs on your machine. AI job application framework built on Claude Code: evaluate postings, tailor CVs, write cover letters, prep interviews. Fork it and own it.
- ai
- ai-agents
- career
- claude-code
- cover-letter
- cv
14
agno-agi/agno★ 42,268 · ⑂ 5,971
Build, run, and manage agent platforms.
- developer-tools
- python
- agents
- ai
- ai-agents
15
langchain-ai/langgraph★ 42,008 · ⑂ 7,091
Build resilient agents.
- agents
- ai
- ai-agents
- chatgpt
- deepagents
- enterprise
16
HKUDS/DeepTutor★ 40,063 · ⑂ 5,035
DeepTutor: Lifelong Personalized Tutoring. https://deeptutor.info/.
- ai-tutor
- deepresearch
- interactive-learning
- large-language-models
- multi-agent-systems
- rag
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17
wshobson/agents★ 39,832 · ⑂ 4,247
Multi-harness agentic plugin marketplace for Claude Code, Codex, Cursor, OpenCode, GitHub Copilot, Google Antigravity, and Pi
- anthropic
- agent-skills
- agentic-ai
- ai-agents
- cursor
- cursor-rules
18
ashishpatel26/500-AI-Agents-Projects★ 37,892 · ⑂ 6,774
The 500 AI Agents Projects is a curated collection of AI agent use cases across various industries. It showcases practical applications and provides links to open-source projects for implementation, illustrating how AI agents are transforming sectors such as healthcare, finance, education, retail, and more.
- ai-agents
- genai
19
VectifyAI/PageIndex★ 35,771 · ⑂ 3,152
📑 PageIndex: Document Index for Vectorless, Reasoning-based RAG
- agentic-ai
- agents
- ai
- ai-agents
- context-engineering
- llm

20
mukul975/Anthropic-Cybersecurity-Skills★ 33,019 · ⑂ 3,998
817 structured cybersecurity skills for AI agents · Mapped to 6 frameworks: MITRE ATT&CK, NIST CSF 2.0, MITRE ATLAS, D3FEND, NIST AI RMF & MITRE F3 (Fight Fraud) · agentskills.io standard · Works with Claude Code, GitHub Copilot, Codex CLI, Cursor, Gemini CLI & 20+ platforms · 29 security domains · Apache 2.0
- ai-agents
- claude-code
- cybersecurity
- incident-response
- mitre-attack
- penetration-testing
21
CloakHQ/CloakBrowser★ 31,586 · ⑂ 2,616
Stealth Chromium that passes every bot detection test. Drop-in Playwright replacement with source-level fingerprint patches. 30/30 tests passed.
- anti-detect
- bot-detection
- browser-automation
- chromium
- cloudflare
- fingerprint
22
virgiliojr94/book-to-skill★ 31,578 · ⑂ 3,273
Turn any technical book PDF into a Claude Code skill — ready to study, reference, and use while you work.
- agent-skills
- ai-agents
- context-engineering
- document-processing
- edtech
- knowledge-base
23
topoteretes/cognee★ 30,860 · ⑂ 3,070
Cognee is the open-source AI memory platform for agents. Give your AI agents persistent long-term memory across sessions with a self-hosted knowledge graph engine.
- ai
- cognitive-architecture
- vector-database
- ai-agents
- graph-database
- ai-memory
24
harvard-edge/cs249r_book★ 28,376 · ⑂ 3,589
Machine Learning Systems: Foundations, Scaling, Agentic AI, and Physical AI (Vols I–IV) • Harvard CS249r | https://mlsysbook.ai
- artificial-intelligence
- cloud-ml
- computer-systems
- courseware
- deep-learning
- edge-machine-learning
25
deepset-ai/haystack★ 26,561 · ⑂ 3,153
Open-source AI orchestration framework for building context-engineered, production-ready LLM applications. Design modular pipelines and agent workflows with explicit control over retrieval, routing, memory, and generation. Built for scalable agents, RAG, multimodal applications, semantic search, and conversational systems.
- semantic-search
- information-retrieval
- ai
- python
- large-language-models
- generative-ai

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Find Python engineers shipping AI agents

The list above ranks the most-starred public Python repositories tagged with the AI agents topic, drawn from the public GitHub graph. Across 1,846 matching repositories, the contributors are a tight cluster of engineers with both Python chops and real AI agents experience.

That overlap is rare. Most Python engineers haven’t shipped AI agents, and most AI agents maintainers don’t write Python. The people on this list’s contributor graph are the ones who do both.

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How this list is built

Refolk searched GitHub for public Python repositories tagged with the AI agents topic, ranked them by stargazer count, and kept those with at least 25 stars. The list refreshes once a day.

Last refreshed: Sun, 20 Sep 2026 14:55:02 GMT

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