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Series C AI companies in San Francisco

Companies building AI products, foundation models, and applied ML platforms. Filtered to Series C-stage companies headquartered in San Francisco.

Built from a search like: “Top Series C AI companies in San Francisco”

Ranked by current headcount across Series C AI companies in San Francisco. Refreshed daily.

  1. 1
    insitro· South San Francisco, California, United States
    • Series C
    • 247 employees
    • Founded 2018
  2. 2
    Arsenal Biosciences, Inc.· South San Francisco, California, United States
    • Series C
    • 203 employees
    • Founded 2019
  3. 3
    Culture Biosciences· South San Francisco, California, United States
    • Series C
    • 79 employees
    • Founded 2016
  4. 4
    Unlearn.AI· San Francisco, California, United States
    • Series C
    • 70 employees
    • Founded 2017
  5. 5
    Terremoto Biosciences· South San Francisco, California, United States
    • Series C
    • 55 employees
    • Founded 2021
  6. 6
    Star Therapeutics· South San Francisco, California, United States
    • Series C
    • 55 employees
    • Founded 2018
  7. 7
    InterVenn Biosciences· South San Francisco, California, United States
    • Series C
    • 38 employees
    • Founded 2017
  8. 8
    Lycia Therapeutics· South San Francisco, California, United States
    • Series C
    • 36 employees
    • Founded 2020
  9. 9
    Soley Therapeutics· South San Francisco, California, United States
    • Series C
    • 36 employees
    • Founded 2020
  10. 10
    Vineti· San Francisco, California, United States
    • Series C
    • 21 employees
    • Founded 2016
  11. 11
    Bluejay Therapeutics· San Francisco Bay Area
    • Series C
    • 21 employees
    • Founded 2020
  12. 12
    Asher Biotherapeutics· South San Francisco, California, United States
    • Series C
    • 17 employees
    • Founded 2019
  13. 13
    Proteolix· South San Francisco, California, United States
    • Series C
    • 12 employees
    • Founded 2003
  14. 14
    BiPar Sciences· South San Francisco, California, United States
    • Series C
    • 7 employees
    • Founded 2004
  15. 15
    Cleave Therapeutics, Inc.· San Francisco, California, United States
    • Series C
    • 3 employees
    • Founded 2011

Find engineers at Series C AI companies in San Francisco

Searching for “engineers at top Series C AI companies in San Francisco” surfaces this slice of the market. The list above ranks AI companies headquartered in San Francisco whose latest disclosed round is Series C, by current headcount, drawn from public LinkedIn and Crunchbase records. With 15 matching companies in our index, this is a tight read on where the AI talent in San Francisco is heating up.

Three filters at once narrows the field hard. The companies that survive all three — Series C, AI, in San Francisco — are usually the most targeted recruiting pool a hiring manager can ask for. Senior engineers, founding designers, and product leads here are about to become AI’s next operators and angel investors.

Refolk converts this list into a live search. Ask for “senior engineers at Series C AI companies in San Francisco hiring” or “founders of Series C AI companies in San Francisco who left in the last year” and Refolk returns a ranked shortlist with the evidence behind each match.

How this list is built

Refolk pulled AI companies headquartered in San Francisco whose latest disclosed funding round is Series C from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 3 employees. The list refreshes once a day.

Last refreshed: Thu, 07 May 2026 07:25:58 GMT

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