Top Series C AI companies

Companies building AI products, foundation models, and applied ML platforms. Filtered to companies whose latest disclosed round is Series C.

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Ranked by current headcount across Series C AI companies. Refreshed monthly.

1
ConcertAI· Cambridge, Massachusetts, United States
ConcertAI orchestrates clinical expertise, real-world data and applied AI to deliver practical intelligence for the demands of treating oncology and other complex diseases.
- Series C
- 857 employees
- Founded 2018
2
Forge Biologics· Columbus, Ohio, United States
Forge, a member of Ajinomoto Bio-Pharma Services, is a gene therapy development engine, focused on enabling access to life changing gene therapies and helping bring them from idea into reality. We partner with innovators in the gene therapy community: scientists, physicians, biotech/pharma companies, and patient groups. We bring expertise in gene therapy manufacturing and therapeutics development to the table, helping champion teams that are navigating the long road from the lab bench to the bedside. With a patients-first approach, we are forging new models for working together to better accelerate these transformative medicines to reach those who need them most.
- Series C
- 438 employees
- Founded 2020
3
BioTissue· Miami, Florida, United States
BioTissue® is a pioneer & proven industry leader in eye care, harnessing the unique power of human birth tissue to support regenerative therapies for Ocular Surface Disease (OSD). Our portfolio of Cryopreserved Amniotic Membrane (CAM) products, including CAM360 AmnioGraftTM, Prokera®, AmnioGraft®, and AmnioGuard®, use our proprietary CryoTek® cryopreservation technology, designed to retain the tissue’s structural & functional integrity. CAM is the only Amniotic Membrane recognized by the FDA for anti-inflammation, anti-scarring, and anti- angiogenesis.1 Eye doctors use CAM360 AmnioGraft & Prokera biologic corneal bandage devices to treat ocular conditions including Neurotrophic Keratitis (NK), Persistent Epithelial Defects (PEDs), and many other Ocular Surface Diseases (OSDs). AmnioGraft can be used for surgical applications ranging from treating burns, primary & recurring pterygiums, and ocular surface reconstruction. AmnioGuard, derived from the umbilical cord, is commonly used by oculoplastic & glaucoma surgeons to provide tectonic support for treating corneal, scleral, socket, fornix, and eyelid cases. BioTissue is committed to empowering healthcare professionals with solutions to deliver optimal patient outcomes by fostering innovation through evidence-based science. Since its inception, clinicians have performed over 1 million human implants using CAM products and published 440 peer-reviewed publications supporting BioTissue’s platform technology.
- Series C
- 374 employees
- Founded 1997
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4
Unknown· Miami, Florida, United States
BioTissue is the leader in innovative technologies using products derived from human amniotic and umbilical cord tissues. Since its inception in 1997, the Company has pioneered the clinical application of human placental tissues – more than 680,000 patients have been treated with BioTissue products and the Company’s groundbreaking scientific and clinical achievements have been documented in more than 380 peer-reviewed publications.
- Series C
- 368 employees
- Founded 2001
5
Vividion Therapeutics, Inc.· San Diego, California, United States
Vividion Therapeutics, Inc. is a biotechnology company focused on transforming the future of human health through the creation of highly selective small molecule medicines that drug traditionally inaccessible targets. The company is advancing a broad, diversified pipeline of multiple, selective small molecule therapeutics for highly sought-after disease-causing target proteins in oncology and immunology. The company’s cutting-edge platform was spun out of the labs of Vividion’s scientific founders, a team of experts in chemical biology and synthetic chemistry from The Scripps Research Institute in La Jolla, CA.
- Series C
- 268 employees
- Founded 2017

6
Colossal Biosciences· Dallas, Texas, United States
Making extinction a thing of the past.Colossal is a breakthrough bioscience and genetic engineering company that builds radical new technologies to advance the field of genomics. Colossal creates disruptive technologies for extinct species restoration, critically endangered species protection and the repopulation of critical ecosystems that support the continuation of life on Earth. The company is the first to apply CRISPR technology for the purposes of species de-extinction. Colossal is accepting humanity’s duty to restore Earth to a healthier state, while also solving for the future economies and biological necessities of the human condition through cutting-edge science and technologies.
- Series C
- 267 employees
- Founded 2021
7
ProBio· Piscataway, New Jersey, United States
ProBio is a global contract development and manufacturing (CDMO) organization, which aims to accelerate the manufacturing of life-changing drugs, discover novel therapeutic targets, and develop innovative therapeutic approaches to manufacture best-in-class DNA, RNA, and protein-based therapeutics. As a global partner, ProBio brings together multi-disciplinary expertise to accelerate the manufacturing of advanced therapies, including biologics, protein and mRNA vaccines, viral vectors, antibody-drug conjugates and drug discovery services. We aid you in realizing the potential of your breakthrough discovery to treat diseases and improve lives. Let us accelerate your path to market with the greatest chance of success!
- Series C
- 251 employees
- Founded 2020
8
Umoja Biopharma· Seattle, Washington, United States
Umoja is developing a new approach to immunotherapy that aims to retool a patient’s immune system in vivo, enhancing the body’s natural capacity to fight diseases.
- Series C
- 250 employees
- Founded 2019
9
Vazyme· Nanjing, Jiangsu, China
Vazyme (688105.SH) is a global biotech supplier dedicated to advancing life science through innovative enzyme technology and continuously expanding the application fields of core technologies in life science, in vitro diagnostics, bio-medicine, and others. To meet the varying needs of our customers and partners, we have developed over 1,000 types of genetically engineered recombinant enzymes, over 3,000 types of high-performance materials, and nearly 3,000 end products. By upholding rigorous quality standards, producing all molecular materials in-house, and following GMP grade quality control processes, we guarantee a consistent and dependable supply to our global customers.Vazyme has served customers in over 60 countries. Its international reach includes more than 9 subsidiaries, supported by 6 major global warehouses and 17 strategically located satellite warehouses.Our mission is to empower our customers to advance the innovation of science and health. Moving forward, we remain steadfastly committed to enhancing public health, helping humanity overcome major illnesses, and fostering collaborations towards a healthier future.
- Series C
- 242 employees
- Founded 2012
10
Clinipace· Morrisville, North Carolina, United States
Caidya is a multi-therapeutic clinical research organization (CRO) serving innovators worldwide. Focused on delivery excellence and an elevated customer experience, Caidya offers a wide range of clinical services and vast therapeutic expertise, supporting its partners from pre-IND strategy, through clinical development to submission and post-marketing surveillance. Caidya leverages industry-leading and proprietary clinical technology to ensure trial transparency and data-driven decision-making. Formed in 2021 following the merger of leading CROs, dMed and Clinipace, Caidya has nearly 1,800 employees in 30+ countries throughout the world.
- Series C
- 235 employees
- Founded 2003

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Find engineers and founders at Series C AI companies

Series C AI companies are some of the most active hirers in the market. The list above ranks the largest AI companies whose latest disclosed round is Series C, by current headcount, drawn from public LinkedIn and Crunchbase records. Across 274 matching companies, you’ll find senior engineers, founding designers, and operators worth tracking.

Companies at this stage in AI share a profile: a working product, fresh capital, and a hiring plan that wants senior people yesterday. Looking at headcount, last round, and HQ side by side gives you a quick read on where AI talent is concentrating right now.

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How this list is built

Refolk pulled AI companies whose latest disclosed funding round is Series C from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 5 employees. The list refreshes monthly.

Last refreshed: Thu, 15 Oct 2026 13:40:20 GMT

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The list draws on the public company graph - headcount and growth signals, funding history, and recency. The criteria chips at the top show exactly which filters produced it, and the methodology section explains the ranking.

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