Late-stage venture AI companies in San Francisco

Companies building AI products, foundation models, and applied ML platforms. Filtered to Late-stage venture-stage companies headquartered in San Francisco.

Edit the query above, or pick a refinement. 500 free credits on sign-up, no card needed.

Built from a search like: “Top Late-stage venture AI companies in San Francisco”

Ranked by current headcount across Late-stage venture AI companies in San Francisco. Refreshed daily.

1
OpenAI· San Francisco, California, United States
OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. AI is an extremely powerful tool that must be created with safety and human needs at its core. OpenAI is dedicated to putting that alignment of interests first — ahead of profit.To achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity. Our investment in diversity, equity, and inclusion is ongoing, executed through a wide range of initiatives, and championed and supported by leadership.At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.
- Series unknown
- 10.5k employees
- Founded 2015
2
Cytovale· South San Francisco, California, United States
Cytovale is a medical diagnostics company focused on providing a more rapid and insightful way to diagnose fast-moving and immune-mediated diseases. Our FDA cleared IntelliSep test is pioneering a new way of quickly and accurately analyzing white blood cells to stratify a patient’s risk of sepsis by performing a biomechanical evaluation of white blood cells collected from a standard blood draw in under 10 minutes. Cytovale’s first market application will be for sepsis, one of the fastest-moving, most lethal conditions in the world. Sepsis, a dysregulated immune response to infection, is often difficult to quickly and accurately diagnose. Sepsis is the no. 1 cause of death in hospitals, taking the lives of 270,000 people every year in the U.S. – more than opioid overdoses, prostate cancer, and breast cancer combined. Mortality from sepsis increases as much as eight percent with every hour of delayed treatment, and as much as 80 percent of sepsis deaths could be prevented with rapid diagnosis and treatment, making early detection essential. Cytovale aims to provide critical insight for early identification of patients at risk of having sepsis, in the time needed for it to be useful.Follow us on Twitter: twitter.com/cytovale
- Series unknown
- 120 employees
- Founded 2013
3
Ossium Health· San Francisco, California, United States
Our mission is to improve the health, vitality, and longevity of human beings through bioengineering.Who we are:At Ossium, we believe that science is humanity’s best weapon in the fight against disease, and we embrace the challenge of mobilizing the world’s healthcare ecosystem to win that fight. In pursuit of this goal, we empower our employees, maintain the highest standards of excellence, and are a force for good.Values we live by:ImpactWe are mission-driven and results-oriented. We believe that a healthier world is a better one and that our work should drive positive change.TruthEmbracing the truth empowers us to learn from both our successes and our mistakes. We follow the data wherever it leads.OwnershipWe hold ourselves and each other to the highest bar. We care deeply about the work we do.GritEach obstacle we encounter in pursuit of a healthier future only sharpens our resolve. We understand that our vision is worth fighting for.
- Series unknown
- 103 employees
- Founded 2016
Live search
This list is a starting point
I can run a natural-language search across LinkedIn, GitHub, and the open web. Fire one of these, or edit the box up top to match exactly who you're after.
- Engineers at top Late-stage venture AI companies in San FranciscoRun
- Founders of Late-stage venture AI companies in San FranciscoRun
500 free credits on sign-up, no card needed.
4
Decipher by Veracyte· South San Francisco, California, United States
Veracyte offers Decipher genomic tests for urologic cancers.
- Series unknown
- 98 employees
- Founded 2008
5
Mission Bio· South San Francisco, California, United States
Mission Bio is a company of passionate people dedicated to solving complex biological problems with precision engineering, innovative biochemistry, and supported bioinformatics. In 2014, the company was spun out of Adam Abate’s lab for high-throughput biology at the University of California, San Francisco (UCSF). Mission Bio’s precision genomics platform is based on the pioneering droplet microfluidics work of Abate and his team.Our mission is to help researchers and clinicians unlock single-cell biology to enable the discovery, development, and delivery of precision medicine.Visit missionbio.com to learn more.
- Series unknown
- 89 employees
- Founded 2014

6
Cartography Biosciences· South San Francisco, California, United States
Building a smarter roadmap for precision therapeutics.
- Series unknown
- 66 employees
- Founded 2020
7
TRexBio· South San Francisco, California, United States
TRexBio is a clinical-stage biotechnology company discovering and developing immunoregulatory medicines based on tissue Treg biology by leveraging cutting-edge computational biology tools, a focus on human tissue, and deep immunobiology expertise. The company’s Deep Biology platform maps human tissue Treg behavior to disease processes to identify and characterize novel targets for therapeutic intervention. Our lead program TRB-061, currently in a Ph1 clinical trial for atopic dermatitis, is a novel TNFR2-selective agonist designed to activate and expand effector Tregs in the tissue and restore immune balance in inflammatory diseases. TRexBio is headquartered in South San Francisco, California. For more info, visit www.trex.bio.
- Series unknown
- 62 employees
- Founded 2018
8
SillaJen· San Francisco, California, United States
SillaJen Biotherapeutics, Inc. is located in San Francisco, one of the largest and most innovative biotech clusters in the world. Sillajen Biotherapeutics focuses on the research, development and manufacturing of oncolytic viruses to treat cancer; we are responsible for Clinical Operations, Regulatory Affairs, Research and Development, Manufacturing, Alliance Management and Accounting for clinical trials.SillaJen, Inc. is a South Korean based biotechnology company headquartered in Busan South Korea, with satellite offices in Seoul, South Korea and San Francisco, CA. The company is focused on the development and commercialization of oncolytic immunotherapy products using the SOLVETM platform, including its lead product Pexa-Vec, which is currently in Phase 3 trials for the treatment of advanced primary liver cancer. Additional information about SillaJen is available at www.sillajen.com.
- Series unknown
- 30 employees
- Founded 2003
9
Syapse· San Francisco, California, United States
To achieve more precise care for every patient, we need to transform real-world evidence into insights that can directly impact care. At Syapse, that is real-world care. It’s found in the way we empower healthcare organizations to work together in active, transparent partnerships, delivering complete patient insights to answer the questions that matter and then purposefully applying it at where patients receive care – driving real impact for cancer patients and beyond.
- Series unknown
- 29 employees
- Founded 2008
10
Acelot· South San Francisco, California, United States
Acelot is treating functional protein misfolding diseases where the appropriate therapeutic mechanism is a restoration of the normal protein homeostasis. Functional misfolded proteins are found in various diseases such as ALS, FTD, Parkinson’s, diabetes and cancer. Acelot’s platform combines generative AI, molecular dynamics simulations and proprietary assays to discover small molecules that restore the homeostasis of misfolded proteins in various diseases. We have a pipeline of hit-to-lead discovery compounds across multiple indications, along with an IND-ready candidate for ALS. Our platform was invented by UCSB Computer Science Professor Dr. Ambuj Singh. Acelot’s first development candidate, ACE-2223, is a first-in-class orally bioavailable small molecule that will undergo IND-enabling studies in 2024. ACE-2223 disrupts the misfolded forms of TDP43 and restores functional TDP43. It acts upon the misfolded conformations of TDP43 found across various patient populations, including ALS, FTD and Alzheimer’s. ACE-2223 has excellent brain penetrance and ADME properties. Acelot also has a robust discovery pipeline.
- Series unknown
- 28 employees
- Founded 2006

Reveal 30 more·500 free credits, no card

Find engineers at Late-stage venture AI companies in San Francisco

Searching for “engineers at top Late-stage venture AI companies in San Francisco” surfaces this slice of the market. The list above ranks AI companies headquartered in San Francisco whose latest disclosed round is Late-stage venture, by current headcount, drawn from public LinkedIn and Crunchbase records. With 35 matching companies in Refolk’s index, this is a tight read on where the AI talent in San Francisco is heating up.

Three filters at once narrows the field hard. The companies that survive all three - Late-stage venture, AI, in San Francisco - are usually the most targeted recruiting pool a hiring manager can ask for. Senior engineers, founding designers, and product leads here are about to become AI’s next operators and angel investors.

Refolk converts this list into a live search. Ask for “senior engineers at Late-stage venture AI companies in San Francisco hiring” or “founders of Late-stage venture AI companies in San Francisco who left in the last year” and Refolk returns a ranked shortlist with the evidence behind each match.

How this list is built

Refolk pulled AI companies headquartered in San Francisco whose latest disclosed funding round is Late-stage venture from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 3 employees. The list refreshes once a day.

Last refreshed: Wed, 05 Aug 2026 13:49:04 GMT

Search this list

Need an even more specific search?

Refolk runs natural-language searches across LinkedIn, GitHub, and the open web. Try one of these:

500 free credits on sign-up, no card needed.

Related lists

See all company lists.

Slice this list a different way

Common questions

How is this ranking built?

The list draws on the public company graph - headcount and growth signals, funding history, and recency. The criteria chips at the top show exactly which filters produced it, and the methodology section explains the ranking.

How fresh is the data?

The underlying index updates continuously and this page re-renders at least daily. Last refreshed: Wed, 05 Aug 2026 13:49:04 GMT.

Can I get the full list of 35 companies?

Yes. This page shows the top of the ranking; sign up and I'll run the search live for the complete, current list. You start with 500 free credits, no card required.

Can I find the people inside these companies?

Yes. Ask in plain English - for example "engineering leaders at these companies who joined in the last year" - and I return the specific people, with context on each.

Try it on your own search

Stop building boolean strings. Just describe the person.

Type one sentence and I plan the search, read GitHub, public LinkedIn and Crunchbase records, and the open web live, then hand back a ranked shortlist with the reasoning behind every name. No filters to learn, no export to clean up, no sales call to sit through.

One sentence in, a ranked shortlist out. No boolean, no filters, no seat to buy.
Read live at search time, not from a database that went stale last quarter.
Watch every step as it runs, and see why each name made the list.

500 free credits on sign-up. No card, no demo call. See real searches.

This list is a starting point