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Top AI companies in Seattle

Companies building AI products, foundation models, and applied ML platforms. Filtered to companies headquartered in Seattle.

Built from a search like: “Top AI companies in Seattle”

Ranked by current headcount across AI companies headquartered in Seattle. Refreshed daily.

  1. 1
    Allen Institute· Seattle, Washington, United States
    • Grant
    • 1.4k employees
    • Founded 2003
  2. 2
    Just - Evotec Biologics· Seattle, Washington, United States
    • 631 employees
    • Founded 2014
  3. 3
    University of Washington School of Public Health· Seattle, Washington, United States
    • Grant
    • 347 employees
    • Founded 1967
  4. 4
    Benaroya Research Institute· Seattle, Washington, United States
    • Grant
    • 309 employees
    • Founded 1956
  5. 5
    Institute for Systems Biology (ISB)· Seattle, Washington, United States
    • Grant
    • 274 employees
    • Founded 2000
  6. 6
    Sana Biotechnology, Inc.· Seattle, Washington, United States
    • Post-IPO equity
    • 254 employees
    • Founded 2018
  7. 7
    NanoString Technologies, Inc.· Seattle, Washington, United States
    • Post-IPO debt
    • 247 employees
    • Founded 2003
  8. 8
    Kaiser Permanente Washington Health Research Institute· Seattle, Washington, United States
    • 225 employees
    • Founded 1983
  9. 9
    Umoja Biopharma· Seattle, Washington, United States
    • Series C
    • 223 employees
    • Founded 2019
  10. 10
    Omeros Corporation· Seattle, Washington, United States
    • Post-IPO equity
    • 222 employees
    • Founded 1994
  11. 11
    Institute for Protein Design, University of Washington· Seattle, Washington, United States
    • 200 employees
    • Founded 2012
  12. 12
    Center for Infectious Disease Research· Seattle, Washington, United States
    • Grant
    • 172 employees
    • Founded 1976
  13. 13
    Applied Physics Laboratory-UW· Seattle, Washington, United States
    • 157 employees
  14. 14
    FRED HUTCHINSON CANCER RESEARCH· Seattle, Washington, United States
    • 141 employees
  15. 15
    Blue Marble Space Institute of Science· Seattle, Washington, United States
    • Grant
    • 133 employees
    • Founded 2009
  16. 16
    Parse Biosciences· Seattle, Washington, United States
    • Series C
    • 128 employees
    • Founded 2018
  17. 17
    NorthWest Research Associates· Seattle, Washington, United States
    • 127 employees
    • Founded 1984
  18. 18
    Sage Bionetworks· Seattle, Washington, United States
    • 125 employees
    • Founded 2009
  19. 19
    The Institute for Corporate Productivity (i4cp)· Seattle, Washington, United States
    • Convertible note
    • 120 employees
    • Founded 1962
  20. 20
    CoMotion at University of Washington· Seattle, Washington, United States
    • 116 employees
    • Founded 1982
  21. 21
    Lumen Bioscience· Seattle, Washington, United States
    • Series C
    • 107 employees
    • Founded 2017
  22. 22
    Cancer Research And Biostatistics (CRAB)· Seattle, Washington, United States
    • 95 employees
    • Founded 1997
  23. 23
    Juno Therapeutics, Inc.· Seattle, Washington, United States
    • Series B
    • 93 employees
    • Founded 2013
  24. 24
    GH Labs· Seattle, Washington, United States
    • 82 employees
    • Founded 2020
  25. 25
    Discovery Institute· Seattle, Washington, United States
    • 79 employees
    • Founded 1990

Find engineers at AI companies in Seattle

Seattle has long been a hub for AI, and the list above ranks the largest AI companies headquartered there by current headcount, drawn from public LinkedIn and Crunchbase records. With 141 matching companies in our index, this is a good map of where the AI talent in Seattlelives — useful whether you’re recruiting, partnering, or sizing a market.

The biggest AI companies in Seattle tend to be the gravitational centres for specialised talent — senior engineers, ML researchers, applied scientists, designers — while the smaller ones compete on speed, equity, and proximity to founders.

Refolk converts this list into a live search. Ask for “AI engineers in Seattlehiring senior staff” or “founders of AI companies in Seattlewho left in the last 12 months” and Refolk returns a ranked shortlist with the evidence that earned each person a spot.

How this list is built

Refolk pulled AI companies headquartered in Seattle from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 10 employees. The list refreshes once a day.

Last refreshed: Thu, 07 May 2026 06:05:07 GMT

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