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Top AI companies in Boston

Companies building AI products, foundation models, and applied ML platforms. Filtered to companies headquartered in Boston.

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Built from a search like: “Top AI companies in Boston”

Ranked by current headcount across AI companies headquartered in Boston. Refreshed daily.

  1. 1
    Vertex Pharmaceuticals· Boston, Massachusetts, United States
    • post ipo secondary
    • 6.4k employees
    • Founded 1989
  2. 2
    Pacific Northwest National Laboratory· Richland, Washington, United States
    • Grant
    • 6.3k employees
    • Founded 1965
  3. 3
    Alexion Pharmaceuticals, Inc.· New Boston, Massachusetts, United States
    • Post-IPO equity
    • 5.1k employees
    • Founded 1992
  4. 4
    argenx· Boston, Massachusetts, United States
    • Post-IPO equity
    • 2.2k employees
    • Founded 2008
  5. 5
    Foundation Medicine· Boston, Massachusetts, United States
    • Series B
    • 1.8k employees
    • Founded 2010
Reveal 289 more·100 free credits, no card

Find engineers at AI companies in Boston

Boston has long been a hub for AI, and the list above ranks the largest AI companies headquartered there by current headcount, drawn from public LinkedIn and Crunchbase records. With 294 matching companies in our index, this is a good map of where the AI talent in Bostonlives - useful whether you’re recruiting, partnering, or sizing a market.

The biggest AI companies in Boston tend to be the gravitational centres for specialised talent - senior engineers, ML researchers, applied scientists, designers - while the smaller ones compete on speed, equity, and proximity to founders.

Refolk converts this list into a live search. Ask for “AI engineers in Bostonhiring senior staff” or “founders of AI companies in Bostonwho left in the last 12 months” and Refolk returns a ranked shortlist with the evidence that earned each person a spot.

How this list is built

Refolk pulled AI companies headquartered in Boston from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 10 employees. The list refreshes once a day.

Last refreshed: Sun, 21 Jun 2026 10:37:10 GMT

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