Top Series B companies in Boston

Foundation Medicine is a global, patient-focused precision medicine company delivering high-quality, transformative diagnostic solutions in cancer and other diseases. We provide tests and solutions to transform care throughout a patient’s experience, from defining a diagnosis to determining the appropriate treatment to ongoing monitoring. We help accelerate the development of new personalized therapies by leveraging our vast knowledge of precision medicine, real world data and AI-powered tools, expanding the information our diagnostic solutions provide to enable improved outcomes for patients. Every day, we are inspired to think differently to transform the lives of people living with cancer and other diseases. For more information, visit us at www.FoundationMedicine.com.Community Guidelines: bit.ly/FMICommunityGuidelines

• Series B
• 1.8k employees
• Founded 2010

The future of work demands smarter applications. Mendix is where you build, deploy, and orchestrate the intelligent solutions the human-AI workforce relies on—with built-in shared context and governance that connects everything perfectly.Create production-ready agentic applications and AI agents that understand your business inside and out. They're built on your data, follow your logic, and fit seamlessly into your existing architecture. Connect agents across all your business systems, then orchestrate workflows where AI handles the routine and humans step in exactly when they're needed; with full context already in hand.The difference is simple: most enterprise AI projects stall out because companies treat governance, integration, and trust as afterthoughts. We flip that script. With Mendix, every agent decision, human approval, and AI output is automatically traceable and compliant from the start. That's what separates AI experiments from AI that actually runs your business.Whether you're launching your first intelligent application or scaling an organization-wide portfolio, leading companies worldwide trust Mendix to bridge the gap between human expertise and AI capabilities—creating workforces that don't just use technology, they orchestrate it.Ready to build intelligent applications that work the way you do?Mendix is a Siemens business.

• Series B
• 968 employees
• Founded 2005

Lusha is the B2B data and sales intelligence system used by sales, marketing, recruiting, RevOps teams, and AI agents to find contacts, enrich records, and track real-world buying signals. It works with your CRM, automation tools, and existing GTM stack. 300M+ business contacts and 30M+ company profiles across North America, EMEA, APAC, and LATAM. Email verification at 95–98% by region. Direct dial accuracy at 90%+. 7M new signals processed every week — funding rounds, leadership changes, hiring surges, and more. 1.2B+ data points processed daily. Lusha also identifies anonymous website visitors and matches them to verified company and contact records.Lusha Deep Intel — uses your ICP, CRM, and pipeline data to prioritize accounts, identify buying groups, and surface the contacts worth reaching out to. It gets more accurate as it learns your business. For RevOps, that means a CRM that stays clean without manual work. For sales, account lists grounded in real pipeline context. For marketing, ABM campaigns built on verified data and intent signals. For recruiting teams, faster sourcing with verified contact data across every region.Available via Lusha Workspace, Chrome Extension, API, MCP, Claude, ChatGPT and more.Used by 280,000+ revenue teams including Google, Zendesk, and Yotpo. GDPR and CCPA compliant. Independently audited under ISO 27701, ISO 27001, and SOC 2 Type II. Validated by TrustArc and ePrivacyseal.Sign-up for free. Paid plans unlock higher volume, additional signal types, and the full depth of intelligence.

• Series B
• 353 employees
• Founded 2016

iboss is a leading Zero Trust Secure Access Service Edge (SASE) cloud security platform that consolidates network and security technologies into a single cloud-based service. By integrating VPN, Secure Web Gateway (SWG), SD-WAN, branch firewalls, Browser Isolation, and Cloud Access Security Broker (CASB) capabilities, iboss replaces legacy solutions to enhance security, reduce complexity, and lower costs. Utilizing Zero Trust Network Access (ZTNA), iboss grants users access only to the applications they need based on their identity, minimizing risks of breaches and data loss. As a unified network and security service with a single-pane-of-glass management console, iboss empowers organizations to enhance security, improve user experience, and support a distributed workforce in today's evolving digital landscape. Leveraging a purpose-built cloud architecture backed by 230+ issued and pending patents and more than 100 points of presence globally, iboss processes over 150 billion transactions daily, blocking 4 billion threats per day. More than 4,000 global enterprises trust the iboss platform to support their modern workforces, including a large number of Fortune 50 companies. iboss was named a Leader in the IDC MarketScape for Worldwide ZTNA, one of the Top 25 Cybersecurity Companies by The Software Report, one of the 25 highest-rated Private Cloud Computing Companies to work for by Battery Ventures, CRN’s top 20 Coolest Cloud Security Companies, and is one of Inc.’s 2024 Best Workplaces.

• Series B
• 353 employees
• Founded 2003

Form Health is the national leader in science-based obesity and cardiometabolic care. Our clinical care model consists of one-on-one, personalized care from a dedicated ABOM-certified physician and a CSOWM-certified Registered Dietitian, who develop individualized treatment plans that address behavioral health, nutrition, physical activity, and include a prescription for FDA-approved medication, if appropriate. Form Health keeps safety, efficacy, and outcomes at the forefront as we incorporate the latest research and science into our approach. This means we’re always innovating, constantly getting smarter about the science of obesity care, relentlessly focusing on exceptional results, and calling out harmful practices that hold back progress. The result is life-changing outcomes for our patients and meaningful ROI for our enterprise partners. Form Health is in-network with national health plans. Learn more at formhealth.co.

• Series B
• 257 employees
• Founded 2019