Seed Healthtech companies in San Francisco

Companies building software and devices for clinicians, patients, and payers. Filtered to Seed-stage companies headquartered in San Francisco.

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Built from a search like: “Top Seed Healthtech companies in San Francisco”

Ranked by current headcount across Seed Healthtech companies in San Francisco. Refreshed monthly.

1
Institute on Aging· San Francisco, California, United States
Institute on Aging (IOA) believes the future should be something to look forward to, at every age. We bring together pioneering experts, seasoned champions and hands-on caregivers to make growing older better for Bay Area seniors and their families.As the leading advocate for older adults and those who care for them, we offer a broad spectrum of services and support to help seniors maintain their independence as long it is safe to do so. In addition to providing home care and case management services, we operate San Francisco's Elder Abuse Prevention Program; The Friendship Line, a free 24-hour suicide prevention "warm" line for seniors; adult day care centers for adults experiencing Alzheimer's and dementia; the Program of All-Inclusive Care for the Elderly (PACE), which provides medical care, physical therapy and enrichment activities for older adults; CONNECT, a free community referral service for all things elder. Institute on Aging is located in San Francisco and works with clients in San Francisco, Marin, San Mateo, Santa Clara, East Bay, the Peninsula, and San Bernadino/Riverside County.
- Seed
- 472 employees
- Founded 1985
2
Coa· San Francisco, California, United States
We're building a better employee mental health benefit that your team will actually use. Welcome to Coa, your team's online gym for mental health offering live, online emotional fitness workshops & on-demand learning. We teach interactive classes on resilience, self-awareness, leadership, communication, managing burnout, psychological safety and more. Help your team become more engaged, effective, and connected with Coa. Learn more at joincoa.com/employers
- Seed
- 420 employees
- Founded 2019
3
Mochi Health· San Francisco, California, United States
At Mochi Health, we're using AI to build a world where healthcare actually works for the people in it.We're an AI-first telehealth marketplace, connecting patients, providers, and pharmacies on one platform where patients choose their own care and providers practice without the friction that slows medicine down. The intelligence behind it is ours, built in house, from the tools that give our providers their time back to the technology that makes care feel personal at scale.This is what healthcare looks like when it's designed around real life: accessible, intuitive, and built to fit the way people actually live. We believe the future of medicine is personal, and we're building it for the hundreds of thousands of patients who trust us, and the providers who care for them.
- Seed
- 353 employees
- Founded 2022
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4
Wellnite· San Francisco, California, United States
Wellnite helps corporations and small business owners increase revenue and employee retention by providing mental health services to employees. We offer prescription delivery, therapists and doctors 24/7 to your employees. Email us: hello@wellnite.com
- Seed
- 224 employees
- Founded 2019
5
Wisp· San Francisco, California, United States
Today, Wisp is the largest dedicated women’s tele-health provider in the U.S., serving more than 1.8 million patients nationwide. Through discreet online care and a comprehensive suite of first-to-market products, Wisp supports women’s health at every stage of life—from birth control and fertility to menopause, STI testing, and beyond.Whether patients require a fast, reliable prescription, a trusted over-the-counter solution, or ongoing longitudinal care, Wisp connects them with licensed providers in real time—helping them navigate symptoms safely and return to wellness with confidence.Working at Wisp -- Remote-first: Work from anywhere in the worldFlexible schedules: Balance work and life seamlesslyMission-driven: Make an impact in advancing women’s healthcareJoin Wisp—and be part of a company reshaping the future of women’s health through innovation, inclusivity, and care that meets patients wherever they are.
- Seed
- 105 employees
- Founded 2018

6
Biome Analytics· San Francisco, California, United States
About Biome AnalyticsBiome Analytics helps hospitals and health systems transform cardiovascular care through a technology-driven, human-enabled performance platform. Our software delivers data-powered insights that support clinical, operational, and financial excellence across the entire cardiovascular service line.We integrate advanced analytics, benchmarking, and AI-enhanced tools with deep healthcare expertise to help teams identify opportunities, track performance, and accelerate meaningful change. By combining registry, EMR, administrative, and cost data, Biome enables scalable, actionable insights that improve outcomes and efficiency.Biome supports programs across:• Interventional and Structural Heart• Electrophysiology• Vascular Surgery• Heart Failure and Chronic Disease• Mechanical Circulatory Support• Non-Invasive Cardiology and ImagingOur clients use Biome to:✔ Improve clinical outcomes and accreditation readiness✔ Reduce unwarranted variation and optimize care pathways✔ Strengthen documentation and risk adjustment accuracy✔ Track length of stay, blood use, and readmissions✔ Understand margins and cost of care by procedure and populationBy integrating AI into our platform, Biome equips cardiovascular teams with smart tools that surface risks, prioritize focus areas, and support faster decision-making. Combined with expert guidance, we help our partners deliver sustainable performance improvement at scale.Let’s build the future of heart care, together.www.biome.io
- Seed
- 75 employees
- Founded 2013
7
Fold Health· San Francisco, California, United States
Fold Health helps outcomes-focused care teams scale person-centered care. Our AI-powered care operations platform brings patient intelligence, prioritized workflows, outreach, coordination, and automation into one place helping teams identify who needs attention, take the right next action, and improve outcomes without increasing administrative burden.
- Seed
- 73 employees
- Founded 2021
8
Bristle· San Francisco, California, United States
Bristle helps you measure, understand, and improve your oral health. Our mouths are the gateways to our bodies and play a critical role in our overall health. Oral disease like cavities and gum disease are tied to increased risk for conditions including Alzheimer's, diabetes, and heart disease. There has not been a way to measure oral health. Dental care today revolves around diagnosing and treating oral disease but does little in the way of prevention and whole-body health. Bristle analyzes the oral microbiome - the makeup of bacteria, fungi, and viruses in saliva - to measure oral health status. Some of these microbes are helpful, and contribute to good oral health while lowering our risk for disease. Other microbes are harmful, directly or indirectly leading to oral and systemic disease. Our test provides you with direct insight into your oral health and risk factors for disease. Based on other factors including your medical history, diet, and hygiene, we pair you with personalized recommendations focused on repairing and maintaining balance in your oral microbiome. We believe that improving oral health is a fundamental step towards improving overall health - and we'd like to help you get here.
- Seed
- 69 employees
- Founded 2020
9
Zen· San Francisco, California, United States
At Zen, we’re on a mission to free the world of physical and mental pain.We envision a world where technology empowers people to be mentally and physically free.We've started by building award-winning posture awareness software applications that gently nudges users when they slouch.We have tens of thousands users and have raised $3.5M from top-tier investors, including Y Combinator, Valor Equity Partners, and more.To go to the next level, we are on a mission to hire a diverse community of people who share a commitment to achieving excellence in their respective lines of work and are excited about the rare opportunity to make an early impact at a high-growth startup.Are you ready to free the world?
- Seed
- 69 employees
- Founded 2020
10
Flint· San Francisco, California, United States
Find what the global health care talent stream can really do. The right staff. Expertise on demand. Find everything you need to optimize your staffing needs — with Flint.
- Seed
- 68 employees
- Founded 2022

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Find engineers at Seed Healthtech companies in San Francisco

Searching for “engineers at top Seed Healthtech companies in San Francisco” surfaces this slice of the market. The list above ranks Healthtech companies headquartered in San Francisco whose latest disclosed round is Seed, by current headcount, drawn from public LinkedIn and Crunchbase records. With 89 matching companies in Refolk’s index, this is a tight read on where the Healthtech talent in San Francisco is heating up.

Three filters at once narrows the field hard. The companies that survive all three - Seed, Healthtech, in San Francisco - are usually the most targeted recruiting pool a hiring manager can ask for. Senior engineers, founding designers, and product leads here are about to become Healthtech’s next operators and angel investors.

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Refolk pulled Healthtech companies headquartered in San Francisco whose latest disclosed funding round is Seed from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 3 employees. The list refreshes monthly.

Last refreshed: Sat, 19 Sep 2026 16:37:37 GMT

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The list draws on the public company graph - headcount and growth signals, funding history, and recency. The criteria chips at the top show exactly which filters produced it, and the methodology section explains the ranking.

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