Andreessen Horowitz portfolio Biotech companies

Multi-stage venture firm investing across consumer, enterprise, fintech, and crypto. Filtered to companies in Biotech.

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Built from a search like: “Andreessen Horowitz-backed Biotech companies”

Ranked by current headcount across Andreessen Horowitz-backed Biotech companies. Refreshed monthly.

1
Flatiron Health· New York, New York, United States
Flatiron Health’s mission is to improve and extend lives by learning from the experience of every person with cancer.
- Series D
- 1.4k employees
- Founded 2012
2
Freenome· Brisbane, California, United States
Freenome is a high-growth biotech company on a mission since 2014 to create tools that empower everyone to prevent, detect, and treat their disease.To achieve this mission, Freenome is developing next-generation blood tests to detect cancer in its earliest, most treatable stages using our multiomics platform and machine learning techniques. Our first blood test will detect early-stage colorectal cancer and advanced adenomas. We have raised more than $1.1 billion from leading investors like Perceptive Advisors, RA Capital Management, Roche Venture Fund, Kaiser Permanente, Novartis and the American Cancer Society’s BrightEdge Ventures. A ‘Freenomer’ is a mission-driven employee who is fueled by the opportunity to make a positive impact on patients' lives, who thrives in a culture of respect and cross collaboration, and whose work makes a significant impact on the company and their career.
- Post-IPO equity
- 411 employees
- Founded 2014
3
Ultima Genomics· Fremont, California, United States
Ultima Genomics is unleashing the power of genomics at scale. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. With humanity on the cusp of a biological revolution, there is a virtually endless need for more genomic information to address biology’s complexity and dynamic change—and a further need to challenge conventional next-generation sequencing technologies. Ultima’s revolutionary new sequencing architecture drives down the costs of sequencing to help overcome the tradeoffs that scientists and clinicians are forced to make between the breadth, depth, and frequency with which they use genomic information. The new sequencing architecture was designed to scale far beyond conventional sequencing technologies, lower the cost of genomic information and catalyze the next phase of genomics in the 21st century.
- Series unknown
- 308 employees
- Founded 2016
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4
Formation Bio· New York, New York, United States
Formation Bio is an AI-native pharma company differentiated by radically more efficient drug development. The company has built proprietary technology platforms to optimize critical aspects of clinical drug development, enabling more efficient trial design, faster trial completion, and higher quality trial data. Formation Bio acquires clinical-stage drugs from pharmaceutical and biotech companies with the goal to develop assets faster, unlock greater value per program and ultimately accelerate access to new treatments for patients.2025 CNBC Disruptor 502025 Fierce 15 Award2024 Endpoints 11 Award
- Series D
- 199 employees
- Founded 2013
5
Maze Therapeutics· South San Francisco, California, United States
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. The company’s pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease. Maze is based in South San Francisco.
- Post-IPO equity
- 161 employees
- Founded 2018

6
Genesis Molecular AI· Burlingame, California, United States
Genesis Molecular AI – headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego and offices in New York – is pioneering foundation models for molecular AI to unlock a new era of drug design and development. We are using a proprietary state-of-the-art generative and predictive AI platform called GEMS (Genesis Exploration of Molecular Space), to accelerate and optimize small molecule drug discovery.The GEMS platform integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. GEMS accelerates hit ID through lead optimization and candidate selection by generating promising molecules for synthesis and experimental testing, and iterating this process through cycles of AI-enabled discovery and optimization.We have leveraged GEMS to build an internal pipeline with multiple programs against high-value targets, including data-poor and canonically undruggable targets where GEMS is uniquely advantaged. In addition, Genesis has signed AI platform collaborations across a range of therapeutic areas including Gilead (2024), and Incyte (2025).Genesis has raised over $300M in funding from top AI, technology and biotech investors, including Andreessen Horowitz, Rock Springs Capital, T. Rowe Price, Fidelity, Radical Ventures, NVentures (NVIDIA's VC arm), BlackRock, and Menlo Ventures. To learn more about Genesis Molecular AI, or current employment opportunities, please visit our website.
- Corporate
- 158 employees
- Founded 2019
7
Nautilus Biotechnology· San Carlos, California, United States
Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, Nautilus (Nasdaq: NAUT) set about solving a vexing problem: how to bring true proteomics to the world in a way that accelerates therapeutic development, dramatically improves medical diagnostics, and makes personalized and predictive medicine a reality.The extraordinary team at Nautilus represents a wide spectrum of disciplines and expertise, including: protein chemists, chip designers, molecular biologists, data scientists, material scientists, biophysicists, optical engineers, microfluidics engineers, bioinformaticists, software engineers, and more.Nautilus is positioned to revolutionize proteomics, transform the way drugs are developed, and significantly improve the way human health is managed.
- Grant
- 151 employees
- Founded 2016
8
Apeel Sciences· Goleta, California, United States
Apeel's evolving technology stack is built on an unprecedented understanding of produce quality and shelf life. This has only deepened as the use of data and technology have given partners a powerful way to accurately and efficiently evaluate produce for ripeness, freshness, and other attributes. Apeel is developing science-backed, technology-supported solutions that help improve the produce experience on shelf.
- Series unknown
- 146 employees
- Founded 2012
9
Curie.Bio· Remote, Oregon, United States
Curie.Bio is a venture capital firm that helps founders discover and develop important new medicines. We do this by investing directly into existing companies, creating focused spinouts, and helping founders build companies from scratch. With $1B under management for seed and Series A rounds, and a 100-person team whose expertise has contributed to more than 40 FDA-approved drugs, we work side by side with founders to reach critical milestones in a highly capital-efficient way.
- Series unknown
- 141 employees
- Founded 2022
10
Asimov· Boston, Massachusetts, United States
Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.
- Series B
- 120 employees
- Founded 2017

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Andreessen Horowitz’s Biotech portfolio

The list above ranks Andreessen Horowitz-backed Biotech companies by current headcount, drawn from public LinkedIn and Crunchbase records. 48 matching companies in Refolk’s index give you a quick read on where Andreessen Horowitz has gone deepest in the Biotech space.

Andreessen Horowitz’s Biotech bets tend to share a thesis. The engineers, ML researchers, and founders inside these companies are often building the same primitives - and they show up in Biotech talent pools across the next decade.

Refolk converts this list into a live search. Ask for “Andreessen Horowitz Biotech companies hiring senior engineers” or “founders of Andreessen Horowitz-backed Biotech companies” and Refolk returns a fresh ranked shortlist.

How this list is built

Refolk pulled Biotech companies whose disclosed Crunchbase investor list includes Andreessen Horowitz, ranked them by current employee count, and kept those with at least 5 employees. The list refreshes monthly.

Last refreshed: Tue, 20 Oct 2026 12:46:55 GMT

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The list draws on the public company graph - headcount and growth signals, funding history, and recency. The criteria chips at the top show exactly which filters produced it, and the methodology section explains the ranking.

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