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Series A Biotech companies in Boston

Companies applying biology, chemistry, and computation to therapeutics and tooling. Filtered to Series A-stage companies headquartered in Boston.

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Built from a search like: “Top Series A Biotech companies in Boston”

Ranked by current headcount across Series A Biotech companies in Boston. Refreshed daily.

  1. 1
    Soufflé Therapeutics· Boston, Massachusetts, United States
    • Series A
    • 85 employees
    • Founded 2021
  2. 2
    Kelonia Therapeutics· Boston, Massachusetts, United States
    • Series A
    • 74 employees
    • Founded 2017
  3. 3
    Manifold Bio· Boston, Massachusetts, United States
    • Series A
    • 68 employees
    • Founded 2020
  4. 4
    Protein Metrics, LLC· Boston, Massachusetts, United States
    • Series A
    • 56 employees
    • Founded 2011
  5. 5
    Spear Bio· Boston, Massachusetts, United States
    • Series A
    • 54 employees
    • Founded 2021
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Find engineers at Series A Biotech companies in Boston

Searching for “engineers at top Series A Biotech companies in Boston” surfaces this slice of the market. The list above ranks Biotech companies headquartered in Boston whose latest disclosed round is Series A, by current headcount, drawn from public LinkedIn and Crunchbase records. With 30 matching companies in our index, this is a tight read on where the Biotech talent in Boston is heating up.

Three filters at once narrows the field hard. The companies that survive all three - Series A, Biotech, in Boston - are usually the most targeted recruiting pool a hiring manager can ask for. Senior engineers, founding designers, and product leads here are about to become Biotech’s next operators and angel investors.

Refolk converts this list into a live search. Ask for “senior engineers at Series A Biotech companies in Boston hiring” or “founders of Series A Biotech companies in Boston who left in the last year” and Refolk returns a ranked shortlist with the evidence behind each match.

How this list is built

Refolk pulled Biotech companies headquartered in Boston whose latest disclosed funding round is Series A from public LinkedIn and Crunchbase records, ranked them by current employee count, and kept those with at least 3 employees. The list refreshes once a day.

Last refreshed: Sun, 21 Jun 2026 11:29:32 GMT

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