Refolk
Open nowEngineering

Senior Software Engineer, Agents

TetraScience · Cambridge, Massachusetts

Location
Cambridge, Massachusetts, United States
Workplace
Remote
Level
Senior
Posted
14 August

About this role

ABOUT TETRASCIENCE

TetraScience is the Scientific Data and AI Company building Tetra OS, the operating system for scientific intelligence. We help the world’s leading life sciences firms turn fragmented scientific data into AI-native assets and scientific workflows that accelerate discovery, development, and manufacturing. TetraScience’s growing ecosystem of strategic partners includes NVIDIA, Databricks, Thermo Fisher Scientific, Snowflake, Google, and Microsoft.

In connection with your candidacy, you will be asked to carefully review “The Tetra Way,” authored by our CEO, Patrick Grady; it is impossible to overstate the importance of this document, and you should take it literally as you decide whether our mission, culture, and expectations are right for you.

The Role

We are seeking a highly skilled Senior .NET Engineer to join our dynamic team. The ideal candidate will have extensive experience in designing and developing high-performance, scalable applications using C#, the .NET Framework, and TypeScript. The role involves implementing automated testing and leveraging GitHub Actions for CI/CD pipelines. The candidate should also be proficient in production debugging and possess excellent communication skills. Knowledge and experience with AWS cloud services are also essential.


What You Will Do

  • High-Performance, Distributed, and Scalable Application Design:
    • Architect, design, and maintain distributed applications, ensuring high performance, scalability, and security.
  • Full-Stack Development:
    • Develop backend services (primarily C#/.NET and TypeScript) and cloud APIs, as well as modern, responsive front-end applications using TypeScript/React.
  • Microservices Architecture:
    • Design and implement loosely coupled, independently deployable services using AWS services such as DynamoDB, RDS, SQS, Lambda, API Gateway, and others.
  • Automated Testing:
    • Create and maintain automated unit, integration, contract, and end-to-end tests across microservices and UI layers.
  • CI/CD Pipelines:
    • Use GitHub Actions to implement and maintain CI/CD pipelines for both backend services and front-end applications.
  • Production Debugging & Optimization:
    • Diagnose and resolve production issues in distributed systems, including service-to-service communication, CPU/memory/network bottlenecks, and AWS service performance.
  • Observability & Operational Excellence:
    • Instrument services using OpenTelemetry (or equivalent) to enable earlier fault detection, clearer alerting, and stronger operational visibility. Contribute to SLO definition and MTTR reduction efforts across the platform.
  • Collaboration & Communication:
    • Work closely with product managers, tech leads, and other engineers to deliver reliable, maintainable, and scalable solutions. Communicate technical decisions clearly to both technical and non-technical stakeholders.

Requirements

What You Will Bring

Required Skills

  • Strong proficiency in backend service development using C#/.NET.
  • Strong proficiency in TypeScript and React for front-end UI.
  • Experience building and operating software in both on-premises/customer-hosted environments and cloud-native multi-tenant environments, with an understanding of how debugging, deployment, and scaling differ between the two.
  • Hands-on experience with AWS DynamoDB, RDS, SQS (or an equivalent cloud provider) in production environments.
  • Experience with microservices patterns (service discovery, API gateway, messaging/queueing, data partitioning).
  • Experience with automated testing at multiple levels.
  • Strong Git skills and hands-on experience with GitHub Actions for CI/CD.
  • Strong troubleshooting skills for distributed systems in production.
  • Solid understanding of cloud-native architecture and AWS best practices.
  • Familiarity with observability tooling and practices (OpenTelemetry, structured logging, distributed tracing, metrics-based alerting) to support proactive issue detection.

Desirable Skills

  • Familiarity with containerization (Docker) and experience defining AWS infrastructure using CloudFormation (or AWS CDK) to support predictable and repeatable environments.
  • Experience with performance tuning and designing scalable solutions.
  • Experience with, or exposure to, scientific instrument software / Chromatography Data Systems (CDS) e.g., Waters Empower, Thermo Chromeleon, Cytiva UNICORN, Agilent OpenLab, along with knowledge of instrument integration pattern and practices is a strong plus.

Soft Skills Needed:

  • Excellent verbal and written communication.
  • Strong collaboration skills in cross-functional teams.
  • Analytical mindset with high attention to detail.

Why TetraScience

  • Mission-driven: your infrastructure directly enables scientific drug development processes that save and extend lives.
  • Builder culture: everyone ships - engineers, managers, and leadership. No passengers.
  • Technically ambitious: we are rebuilding how science-grade data infrastructure works, not deploying off-the-shelf solutions.
  • AI-first: we apply AI across every layer of the platform today, not as a future roadmap item.
  • Competitive compensation, meaningful equity, and strong benefits.

Benefits

  • 100% employer-paid benefits for all eligible employees and immediate family members
  • Unlimited paid time off (PTO)
  • 401K
  • Flexible working arrangements - Remote work
  • Company paid Life Insurance, LTD/STD
  • A culture of continuous improvement where you can grow your career and get coaching

No visa sponsorship is available for this position

The salary range for this position is $170,000-$220,000 USD. The salary range posted reflects our target baseline for this role. Final compensation is determined by a thorough evaluation of factors including the candidate’s specific experience, localized market data, and internal team equity.

As published by TetraScience. Applications are handled on their site.

Skills this posting mentions

Multi Tenant SystemsC#Distributed Systems

About TetraScience

TetraScience is the R&D Data Cloud company with a mission to transform life sciences R&D, accelerate discovery, and improve and extend human life. The Tetra R&D Data Cloud provides life sciences companies with the flexibility, scalability, and data-centric capabilities to enable easy access to centralized, harmonized, and actionable scientific data and is actively deployed across enterprise pharma and biotech organizations. As an open platform, TetraScience has built the largest integration network of lab instruments, informatics applications, CRO/CDMOs, analytics, and data science partners, creating seamless interoperability and an innovation feedback loop that will drive the future of life sciences R&D. For more information, please visit www.tetrascience.com.

All 21 openings at TetraScience

One click, then it is written

Apply to TetraScience with a resume written for this role.

Queue Senior Software Engineer, Agents and I read the posting, rewrite your resume against it, draft the cover letter, and score the fit. Then you press send, or press one button and I fill in TetraScience’s form for you.

  1. 01Drop your resume

    A PDF or a LinkedIn URL. About a minute, once.

  2. 02I rank the openings

    Every weekday morning, the live catalog scored against your history. Up to 20 worth your time, not two hundred links.

  3. 03Each one is written up

    Resume rewritten for the posting, a cover letter, a fit score. Press send, or let me fill in the form.

  • 25 sent a week, free
  • No card
  • Nothing sent until you say so

More roles at TetraScience

See all

Similar roles elsewhere

See more

Put this to work

Paste your career in once. Every application after that is written for you.

Drop a resume or a LinkedIn URL. I rank the live openings against it, rewrite the resume and write a cover letter for the best of them, and fill in the employer's form when you press the button. You read, you decide what goes out.

  1. 01Drop your resume

    A PDF or a LinkedIn URL. About a minute, once.

  2. 02I rank the openings

    Every weekday morning, the live catalog scored against your history. Up to 20 worth your time, not two hundred links.

  3. 03Each one is written up

    Resume rewritten for the posting, a cover letter, a fit score. Press send, or let me fill in the form.

  • New matches ranked and written before you are up.
  • Every bullet stays inside what your history supports. Nothing invented.
  • Queued, submitted, interviewing, offer: one screen, not a spreadsheet.

Free, no card. Up to 25 applications sent a week, and nothing is sent until you say so.

Listed from the job board TetraScience publishes. Refolk is not the employer and does not handle their hiring. Applications go to TetraScience directly.

Hiring at TetraScience? Post this role to the Refolk talent pool for $299, once. No commission, refunded if I find nobody. Post a role for $299